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Anticoagulation Strategies in Venovenous Hemodialysis in Critically Ill Patients: A Five-Year Evaluation in a Surgical Intensive Care Unit
Joint Authors
Bauer, Michael
Sponholz, Christoph
Bayer, Ole
Wurm, Karin
Ebert, Katharina
Kortgen, Andreas
Kabisch, Björn
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Renal failure is a common complication among critically ill patients.
Timing, dosage, and mode of renal replacement (RRT) are under debate, but also anticoagulation strategies and vascular access interfere with dialysis success.
We present a retrospective, five-year evaluation of patients requiring RRT on a multidisciplinary 50-bed surgical intensive care unit of a university hospital with special regard to anticoagulation strategies and vascular access.
Anticoagulation was preferably performed with unfractionated heparin or regional citrate application (RAC).
Bleeding and suspected HIT-II were most common causes for RAC.
In CVVHD mode filter life span was significantly longer under RAC compared to heparin or other anticoagulation strategies ( P = 0.001 ).
Femoral vascular access was associated with reduced filter life span ( P = 0.012 ), especially under heparin anticoagulation ( P = 0.015 ).
Patients on RAC had higher rates of metabolic alkalosis ( P = 0.001 ), required more transfusions ( P = 0.045 ), and showed higher illness severity measured by SOFA scores ( P = 0.001 ).
RRT with unfractionated heparin represented the most common anticoagulation strategy in this study population.
However, patients with bleeding risk and severe organ dysfunction were more likely placed on RAC.
Citrate provided longer filter life spans regardless of vascular access site.
Attention has to be paid to metabolic disturbances.
American Psychological Association (APA)
Sponholz, Christoph& Bayer, Ole& Kabisch, Björn& Wurm, Karin& Ebert, Katharina& Bauer, Michael…[et al.]. 2014. Anticoagulation Strategies in Venovenous Hemodialysis in Critically Ill Patients: A Five-Year Evaluation in a Surgical Intensive Care Unit. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1051131
Modern Language Association (MLA)
Sponholz, Christoph…[et al.]. Anticoagulation Strategies in Venovenous Hemodialysis in Critically Ill Patients: A Five-Year Evaluation in a Surgical Intensive Care Unit. The Scientific World Journal No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1051131
American Medical Association (AMA)
Sponholz, Christoph& Bayer, Ole& Kabisch, Björn& Wurm, Karin& Ebert, Katharina& Bauer, Michael…[et al.]. Anticoagulation Strategies in Venovenous Hemodialysis in Critically Ill Patients: A Five-Year Evaluation in a Surgical Intensive Care Unit. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1051131
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1051131