Renal Function and Ultrasound Imaging in Elderly Subjects
Joint Authors
Zanoli, Luca
Romano, Giulia
Romano, Marcello
Rastelli, Stefania
Rapisarda, Francesco
Fatuzzo, Pasquale
Malaguarnera, Mariano
Castellino, Pietro
Granata, Antonio
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-04
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
We evaluated in elderly subjects (a) the ability of GFR formulas to discriminate chronic kidney disease (CKD), (b) the correlation between renal morphology and function, and (c) the usefulness of combined r-US and GFR formulas to detect CKD.
A total of 72 patients were enrolled (mean age 80 ± 7 years, male sex 44%, serum creatinine 0.98 ± 0.42 mg/dL, and CKD 57%).
Cockcroft-Gault showed the highest sensitivity (78%) and specificity (94%) for CKD and was correlated with kidney volume ( R = 0.68 , P < 0.001 ).
All formulas failed to provide a reliable estimate of GFR.
In multivariate analysis, Cockcroft-Gault < 52 mL/min and kidney sinus section area < 28 cm2 showed the highest accuracy for the identification of CKD subjects (AUC 0.90, P < 0.001 ).
MDRD and CKD-EPI differed significantly for GFR ≥90 mL/min.
Conclusions.
Cockcroft-Gault < 52 mL/min was able to discriminate subjects with CKD but all formulas failed to provide a reliable estimate of GFR.
The combined use of r-US and Cockcroft-Gault formula improved the ability to discriminate CKD in elderly subjects.
American Psychological Association (APA)
Zanoli, Luca& Romano, Giulia& Romano, Marcello& Rastelli, Stefania& Rapisarda, Francesco& Granata, Antonio…[et al.]. 2014. Renal Function and Ultrasound Imaging in Elderly Subjects. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1051242
Modern Language Association (MLA)
Zanoli, Luca…[et al.]. Renal Function and Ultrasound Imaging in Elderly Subjects. The Scientific World Journal No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1051242
American Medical Association (AMA)
Zanoli, Luca& Romano, Giulia& Romano, Marcello& Rastelli, Stefania& Rapisarda, Francesco& Granata, Antonio…[et al.]. Renal Function and Ultrasound Imaging in Elderly Subjects. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1051242
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1051242