![](/images/graphics-bg.png)
The Neuroprotective Effect of Cornus mas on Brain Tissue of Wistar Rats
Joint Authors
Kryczyk, Jadwiga
Berköz, Mehmet
Francik, Renata
Francik, Sławomir
Krośniak, M.
Sanocka, Ilona
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-10-16
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Cornelian cherry (Cornus mas) is a valuable source of phenolic antioxidants.
Flavonoid derivatives as nonenzymatic antioxidants are important in the pathophysiology of many diseases including neurological disorders (e.g., Alzheimer’s disease) or heart disease.
In this study, we examined the effect of an addition of freeze-dried fruit of cornelian cherry on three types of diets: control diet, fructose diet, and diet enriched in fats (high-fat diet).
This effect was studied by determining the following antioxidant parameters in both brain tissue and plasma in rats: catalase, ferric reducing ability of plasma, paraoxonase, protein carbonyl groups, and free thiol groups.
Results indicate that both fructose diet and high-fat diet affect the antioxidant capacity of the organism.
Furthermore, an addition of cornelian cherry resulted in increased activity of catalase in brain tissue, while in plasma it caused the opposite effect.
In turn, with regard to paraoxonase activity in both brain tissue and plasma, it had a stimulating effect.
Adding cornelian cherry to the tested diets increased the activity of PON in both tested tissues.
Moreover, protective effect of fruits of this plant was observed in the process of oxidation of proteins by decreasing levels of protein carbonyl groups and thiol groups in brain tissue as well as in plasma.
American Psychological Association (APA)
Francik, Renata& Kryczyk, Jadwiga& Krośniak, M.& Berköz, Mehmet& Sanocka, Ilona& Francik, Sławomir. 2014. The Neuroprotective Effect of Cornus mas on Brain Tissue of Wistar Rats. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1051326
Modern Language Association (MLA)
Francik, Renata…[et al.]. The Neuroprotective Effect of Cornus mas on Brain Tissue of Wistar Rats. The Scientific World Journal No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1051326
American Medical Association (AMA)
Francik, Renata& Kryczyk, Jadwiga& Krośniak, M.& Berköz, Mehmet& Sanocka, Ilona& Francik, Sławomir. The Neuroprotective Effect of Cornus mas on Brain Tissue of Wistar Rats. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1051326
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1051326