Ophthalmic Drug Dosage Forms: Characterisation and Research Methods
Joint Authors
Baranowski, Przemysław
Karolewicz, Bożena
Gajda, Maciej
Pluta, Janusz
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-18
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
This paper describes hitherto developed drug forms for topical ocular administration, that is, eye drops, ointments, in situ gels, inserts, multicompartment drug delivery systems, and ophthalmic drug forms with bioadhesive properties.
Heretofore, many studies have demonstrated that new and more complex ophthalmic drug forms exhibit advantage over traditional ones and are able to increase the bioavailability of the active substance by, among others, reducing the susceptibility of drug forms to defense mechanisms of the human eye, extending contact time of drug with the cornea, increasing the penetration through the complex anatomical structure of the eye, and providing controlled release of drugs into the eye tissues, which allows reducing the drug application frequency.
The rest of the paper describes recommended in vitro and in vivo studies to be performed for various ophthalmic drugs forms in order to assess whether the form is acceptable from the perspective of desired properties and patient’s compliance.
American Psychological Association (APA)
Baranowski, Przemysław& Karolewicz, Bożena& Gajda, Maciej& Pluta, Janusz. 2014. Ophthalmic Drug Dosage Forms: Characterisation and Research Methods. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-1051385
Modern Language Association (MLA)
Baranowski, Przemysław…[et al.]. Ophthalmic Drug Dosage Forms: Characterisation and Research Methods. The Scientific World Journal No. 2014 (2014), pp.1-14.
https://search.emarefa.net/detail/BIM-1051385
American Medical Association (AMA)
Baranowski, Przemysław& Karolewicz, Bożena& Gajda, Maciej& Pluta, Janusz. Ophthalmic Drug Dosage Forms: Characterisation and Research Methods. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-1051385
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1051385