Genetic Diversity of Echinococcus granulosus in Southwest China Determined by the Mitochondrial NADH Dehydrogenase Subunit 2 Gene
Joint Authors
Wang, Jiahai
Wang, Ning
Hu, Dandan
Zhong, Xiuqin
Wang, Shuxian
Gu, Xiaobin
Peng, Xuerong
Yang, Guangyou
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-30
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
We evaluated genetic diversity and structure of Echinococcus granulosus by analyzing the complete mitochondrial NADH dehydrogenase subunit 2 (ND2) gene in 51 isolates of E.
granulosus sensu stricto metacestodes collected at three locations in this region.
We detected 19 haplotypes, which formed a distinct clade with the standard sheep strain (G1).
Hence, all 51 isolates were identified as E.
granulosus sensu stricto (G1–G3).
Genetic relationships among haplotypes were not associated with geographical divisions, and fixation indices (Fst) among sampling localities were low.
Hence, regional populations of E.
granulosus in the southwest China are not differentiated, as gene flow among them remains high.
This information is important for formulating unified region-wide prevention and control measures.
We found large negative Fu’s Fs and Tajima’s D values and a unimodal mismatch distribution, indicating that the population has undergone a demographic expansion.
We observed high genetic diversity among the E.
granulosus s.
s.
isolates, indicating that the parasite population in this important bioregion is genetically robust and likely to survive and spread.
The data from this study will prove valuable for future studies focusing on improving diagnosis and prevention methods and developing robust control strategies.
American Psychological Association (APA)
Wang, Jiahai& Wang, Ning& Hu, Dandan& Zhong, Xiuqin& Wang, Shuxian& Gu, Xiaobin…[et al.]. 2014. Genetic Diversity of Echinococcus granulosus in Southwest China Determined by the Mitochondrial NADH Dehydrogenase Subunit 2 Gene. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1051409
Modern Language Association (MLA)
Wang, Jiahai…[et al.]. Genetic Diversity of Echinococcus granulosus in Southwest China Determined by the Mitochondrial NADH Dehydrogenase Subunit 2 Gene. The Scientific World Journal No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1051409
American Medical Association (AMA)
Wang, Jiahai& Wang, Ning& Hu, Dandan& Zhong, Xiuqin& Wang, Shuxian& Gu, Xiaobin…[et al.]. Genetic Diversity of Echinococcus granulosus in Southwest China Determined by the Mitochondrial NADH Dehydrogenase Subunit 2 Gene. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1051409
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1051409