Protective Role of Catechin and Quercetin in Sodium Benzoate-Induced Lipid Peroxidation and the Antioxidant System in Human Erythrocytes In Vitro

Joint Authors

Yetuk, Gamze
Pandir, Dilek
Bas, Hatice

Source

The Scientific World Journal

Issue

Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2014-02-12

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Medicine
Information Technology and Computer Science

Abstract EN

The aim of this study was to evaluate the protective effect of catechin and quercetin in sodium benzoate- (SB-) induced oxidative stress in human erythrocytes in vitro.

For this, the effects of SB (6.25, 12.5, 25, 50, and 100 μg/mL), catechin (10 μM), and quercetin (10 μM) on lipid peroxidation (LPO) and the activities of SOD, CAT, GPx, and GST were studied.

Significantly higher LPO and lower activities of antioxidant enzymes were observed with the increasing concentrations of SB.

Catechin or quercetin protected the erythrocytes against SB-induced toxicity only at low concentrations of SB.

The presence of catechin or quercetin at 10 μM have no effect on SB-induced toxicity at high concentrations of SB (50 and 100 μg/mL).

In conclusion, SB may cause oxidative stress as food additive in human erythrocytes in vitro.

So, it appears that our findings provide evidence for the protection of erythrocytes from SB that could be considered for further studies.

American Psychological Association (APA)

Yetuk, Gamze& Pandir, Dilek& Bas, Hatice. 2014. Protective Role of Catechin and Quercetin in Sodium Benzoate-Induced Lipid Peroxidation and the Antioxidant System in Human Erythrocytes In Vitro. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1051441

Modern Language Association (MLA)

Yetuk, Gamze…[et al.]. Protective Role of Catechin and Quercetin in Sodium Benzoate-Induced Lipid Peroxidation and the Antioxidant System in Human Erythrocytes In Vitro. The Scientific World Journal No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1051441

American Medical Association (AMA)

Yetuk, Gamze& Pandir, Dilek& Bas, Hatice. Protective Role of Catechin and Quercetin in Sodium Benzoate-Induced Lipid Peroxidation and the Antioxidant System in Human Erythrocytes In Vitro. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1051441

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1051441