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Protective Role of Catechin and Quercetin in Sodium Benzoate-Induced Lipid Peroxidation and the Antioxidant System in Human Erythrocytes In Vitro
Joint Authors
Yetuk, Gamze
Pandir, Dilek
Bas, Hatice
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
The aim of this study was to evaluate the protective effect of catechin and quercetin in sodium benzoate- (SB-) induced oxidative stress in human erythrocytes in vitro.
For this, the effects of SB (6.25, 12.5, 25, 50, and 100 μg/mL), catechin (10 μM), and quercetin (10 μM) on lipid peroxidation (LPO) and the activities of SOD, CAT, GPx, and GST were studied.
Significantly higher LPO and lower activities of antioxidant enzymes were observed with the increasing concentrations of SB.
Catechin or quercetin protected the erythrocytes against SB-induced toxicity only at low concentrations of SB.
The presence of catechin or quercetin at 10 μM have no effect on SB-induced toxicity at high concentrations of SB (50 and 100 μg/mL).
In conclusion, SB may cause oxidative stress as food additive in human erythrocytes in vitro.
So, it appears that our findings provide evidence for the protection of erythrocytes from SB that could be considered for further studies.
American Psychological Association (APA)
Yetuk, Gamze& Pandir, Dilek& Bas, Hatice. 2014. Protective Role of Catechin and Quercetin in Sodium Benzoate-Induced Lipid Peroxidation and the Antioxidant System in Human Erythrocytes In Vitro. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1051441
Modern Language Association (MLA)
Yetuk, Gamze…[et al.]. Protective Role of Catechin and Quercetin in Sodium Benzoate-Induced Lipid Peroxidation and the Antioxidant System in Human Erythrocytes In Vitro. The Scientific World Journal No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1051441
American Medical Association (AMA)
Yetuk, Gamze& Pandir, Dilek& Bas, Hatice. Protective Role of Catechin and Quercetin in Sodium Benzoate-Induced Lipid Peroxidation and the Antioxidant System in Human Erythrocytes In Vitro. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1051441
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1051441