Aqueous Extract of Red Deer Antler Promotes Hair Growth by Regulating the Hair Cycle and Cell Proliferation in Hair Follicles
Joint Authors
Li, Jing-jie
Li, Zheng
Gu, Li-juan
Wang, Yun-bo
Lee, Mi-ra
Sung, Chang-keun
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-13
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Deer antlers are the only mammalian appendage capable of regeneration.
We aimed to investigate the effect of red deer antler extract in regulating hair growth, using a mouse model.
The backs of male mice were shaved at eight weeks of age.
Crude aqueous extracts of deer antler were prepared at either 4°C or 100°C and injected subcutaneously to two separate groups of mice ( n = 9 ) at 1 mL/day for 10 consecutive days, with water as a vehicle control group.
The mice skin quantitative hair growth parameters were measured and 5-bromo-2-deoxyuridine was used to identify label-retaining cells.
We found that, in both the 4°C and the 100°C deer antler aqueous extract-injection groups, the anagen phase was extended, while the number of BrdU-incorporated cells was dramatically increased.
These results indicate that deer antler aqueous extract promotes hair growth by extending the anagen phase and regulating cell proliferation in the hair follicle region.
American Psychological Association (APA)
Li, Jing-jie& Li, Zheng& Gu, Li-juan& Wang, Yun-bo& Lee, Mi-ra& Sung, Chang-keun. 2014. Aqueous Extract of Red Deer Antler Promotes Hair Growth by Regulating the Hair Cycle and Cell Proliferation in Hair Follicles. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1051455
Modern Language Association (MLA)
Li, Jing-jie…[et al.]. Aqueous Extract of Red Deer Antler Promotes Hair Growth by Regulating the Hair Cycle and Cell Proliferation in Hair Follicles. The Scientific World Journal No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1051455
American Medical Association (AMA)
Li, Jing-jie& Li, Zheng& Gu, Li-juan& Wang, Yun-bo& Lee, Mi-ra& Sung, Chang-keun. Aqueous Extract of Red Deer Antler Promotes Hair Growth by Regulating the Hair Cycle and Cell Proliferation in Hair Follicles. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1051455
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1051455