Reproductive Toxicity of Triptolide in Male House Rat, Rattus rattus

Joint Authors

Singla, Neena
Challana, Swati

Source

The Scientific World Journal

Issue

Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2014-10-13

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Medicine
Information Technology and Computer Science

Abstract EN

The aim of study was to investigate the toxic effect of triptolide fed in bait on reproduction of male house rat, Rattus rattus.

Feeding of cereal based bait containing 0.2% triptolide to male R.

rattus for 5 days in no-choice feeding test, leading to mean daily ingestion of 20.45 mg/kg bw of triptolide, was found effective in significantly ( P ≤ 0.05 ) reducing sperm motility and viability in cauda epididymal fluid by 80.65 and 75.14%, respectively, from that of untreated rats.

Pregnancy rates were decreased by 100% in untreated cyclic female rats paired with male rats treated with 0.2% triptolide.

Present studies suggest the potential of 0.2% triptolide bait in regulating reproductive output of R.

rattus.

American Psychological Association (APA)

Singla, Neena& Challana, Swati. 2014. Reproductive Toxicity of Triptolide in Male House Rat, Rattus rattus. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1051465

Modern Language Association (MLA)

Singla, Neena& Challana, Swati. Reproductive Toxicity of Triptolide in Male House Rat, Rattus rattus. The Scientific World Journal No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1051465

American Medical Association (AMA)

Singla, Neena& Challana, Swati. Reproductive Toxicity of Triptolide in Male House Rat, Rattus rattus. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1051465

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1051465