Formulation Optimization of Arecoline Patches
Joint Authors
Tsai, Pi-Ju
Li, Chi-Lin
Huang, Yaw-Bin
Wu, Pao-Chu
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
The response surface methodology (RSM) including polynomial equations has been used to design an optimal patch formulation with appropriate adhesion and flux.
The patch formulations were composed of different polymers, including Eudragit RS 100 (ERS), Eudragit RL 100 (ERL) and polyvinylpyrrolidone K30 (PVP), plasticizers (PEG 400), and drug.
In addition, using terpenes as enhancers could increase the flux of the drug.
Menthol showed the highest enhancement effect on the flux of arecoline.
American Psychological Association (APA)
Wu, Pao-Chu& Tsai, Pi-Ju& Li, Chi-Lin& Huang, Yaw-Bin. 2014. Formulation Optimization of Arecoline Patches. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1051697
Modern Language Association (MLA)
Wu, Pao-Chu…[et al.]. Formulation Optimization of Arecoline Patches. The Scientific World Journal No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1051697
American Medical Association (AMA)
Wu, Pao-Chu& Tsai, Pi-Ju& Li, Chi-Lin& Huang, Yaw-Bin. Formulation Optimization of Arecoline Patches. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1051697
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1051697
