Correlation of Ischemia-Modified Albumin with SOFA and APACHE II Scores in Preoperative Patients with Colorectal Cancer
Joint Authors
Kotani, Kazuhiko
Gugliucci, Alejandro
Satoh, Masaaki
Horie, Hisanaga
Caccavello, Russell
Takeuchi, Mamoru
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-08
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Purpose.
Critical illnesses are assessed according to the sequential organ failure assessment (SOFA) and acute physiology and chronic health evaluation (APACHE) II.
Circulating ischemia-modified albumin (IMA) is a biomarker generated under ischemic and oxidative conditions and may reflect disease severity in preoperative patients.
This study investigated the correlations of IMA with SOFA and APACHE II scores in inpatients admitted for colorectal surgery.
Methods.
We examined 27 patients with advanced colorectal cancers (mean age 69 years, men/women = 15/12).
Correlations between SOFA and APACHE II scores in addition to preoperative serum IMA and C-reactive protein (CRP) levels were analyzed.
Results.
The mean IMA level was 0.5 AU, and the median CRP level was 0.6 mg/dL.
Median scores for SOFA and APACHE II were 2 and 12 points, respectively.
Significant positive correlations between IMA and SOFA ( r = 0.45 , P < 0.05 ) and IMA and APACHE II ( r = 0.45 , P < 0.05 ) were identified which remained significant in confounder-adjusted analyses.
In contrast, weak correlations were observed between CRP and the SOFA and APACHE II scores.
Conclusions.
The positive correlations between IMA and both SOFA and APACHE II scores suggest that serum IMA measurements reflect the severity of systemic failure in patients admitted for colorectal surgery in the preoperative phase.
American Psychological Association (APA)
Satoh, Masaaki& Kotani, Kazuhiko& Gugliucci, Alejandro& Horie, Hisanaga& Caccavello, Russell& Takeuchi, Mamoru. 2014. Correlation of Ischemia-Modified Albumin with SOFA and APACHE II Scores in Preoperative Patients with Colorectal Cancer. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1051752
Modern Language Association (MLA)
Satoh, Masaaki…[et al.]. Correlation of Ischemia-Modified Albumin with SOFA and APACHE II Scores in Preoperative Patients with Colorectal Cancer. The Scientific World Journal No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1051752
American Medical Association (AMA)
Satoh, Masaaki& Kotani, Kazuhiko& Gugliucci, Alejandro& Horie, Hisanaga& Caccavello, Russell& Takeuchi, Mamoru. Correlation of Ischemia-Modified Albumin with SOFA and APACHE II Scores in Preoperative Patients with Colorectal Cancer. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1051752
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1051752