Characterization of Mycobacterium bovis from Humans and Cattle in Namwala District, Zambia
Joint Authors
Muma, John Bwalya
Johansen, Tone Bjordal
Djønne, Berit
Malama, Sydney
Munyeme, Musso
Mbulo, Grace
Muwonge, Adrian
Godfroid, Jacques
Source
Veterinary Medicine International
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Tuberculosis remains a major public health problem in Zambia.
While human to human transmission of Mycobacterium tuberculosis is of major importance in driving the tuberculosis epidemic, the impact of Mycobacterium bovis transmission from infected cattle is largely unknown.
This cross-sectional study aimed at molecular characterization of M.
bovis in humans and cattle.
A total of 100 human sputum samples and 67 bovine tissues were collected and analyzed for the presence of mycobacteria.
Of 65 human samples that harbored acid fast bacteria (AFB), 55 isolates were obtained of which 34 were identified as M.
tuberculosis and 2 as M.
bovis.
AFB-positive bovine samples ( n = 67 ) yielded 47 mycobacterial isolates among which 25 were identified as M.
bovis and no M.
tuberculosis was found.
Among the M.
bovis isolates, spoligotyping revealed a high homogeneity in genotypes circulating in Namwala district.
Human and cattle isolates shared identical MIRU-VNTR genotypes, suggesting that transmission between the two hosts may occur.
Therefore, this study has documented zoonotic TB in human patients in Namwala district of Zambia.
However, further molecular epidemiological studies in the study area are recommended.
American Psychological Association (APA)
Malama, Sydney& Johansen, Tone Bjordal& Muma, John Bwalya& Munyeme, Musso& Mbulo, Grace& Muwonge, Adrian…[et al.]. 2014. Characterization of Mycobacterium bovis from Humans and Cattle in Namwala District, Zambia. Veterinary Medicine International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1051893
Modern Language Association (MLA)
Malama, Sydney…[et al.]. Characterization of Mycobacterium bovis from Humans and Cattle in Namwala District, Zambia. Veterinary Medicine International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1051893
American Medical Association (AMA)
Malama, Sydney& Johansen, Tone Bjordal& Muma, John Bwalya& Munyeme, Musso& Mbulo, Grace& Muwonge, Adrian…[et al.]. Characterization of Mycobacterium bovis from Humans and Cattle in Namwala District, Zambia. Veterinary Medicine International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1051893
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1051893