Peritoneal Reactivity Evaluation in Horses Subjected to Experimental Small Colon Enterotomy and Treated with Subcutaneous Heparin
Joint Authors
Alonso, Juliana de Moura
Alves, Ana Liz Garcia
Watanabe, Marcos Jun
Rodrigues, Celso Antonio
Hussni, Carlos Alberto
Rodrigues, Karoline Alves
Yamada, Ana Lúcia Miluzzi
Source
Veterinary Medicine International
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-11
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Heparin is routinely administered in postoperative abdominal surgery aiming to prevent adhesions formation; however, there is no consensus indicating its effectiveness.
This study evaluated the effect of heparin on peritoneal reactivity after abdominal surgery, through the association between peritoneal fluid features and ultrasonographic and laparoscopic examination.
Ten adult horses were used: control group (CG) and treated group (TG).
Both groups underwent laparotomy and small colon enterotomy.
TG received subcutaneous heparin at 150 IU/kg every 12 hours for 5 days.
The animals underwent ultrasonography and peritoneal fluid examination prior to enterotomy (M0) 12 hours (M1), 1 day (M2), 2 days (M3), 4 days (M4), 6 days (M5), 10 days (M6), and 14 days after enterotomy (M7) with laparoscopic examination being performed on the fifth postoperative day.
Peritoneal inflammatory response was observed in both groups.
The peritoneal fluid of TG animals showed higher echogenicity during heparin therapy.
No inflammatory difference was observed between groups through peritoneal fluid features, except for the higher D-dimer concentration in CG.
On laparoscopy, slightly diffuse peritoneal reactivity for both groups was observed, being higher for TG.
Laparoscopy and ultrasonography association allowed detailed access to the abdominal cavity.
Ultrasonography assessed the diffuse peritoneal inflammation, and laparoscopy allowed the detailed analysis of the segments.
No gross beneficial reactions resulting from the use of heparin on peritoneal reactivity were observed; however, it was observed by D-dimer evaluation that the TG had less fibrin deposition, which is directly related to a lower rate of abdominal adhesions formation.
American Psychological Association (APA)
Alonso, Juliana de Moura& Rodrigues, Karoline Alves& Yamada, Ana Lúcia Miluzzi& Watanabe, Marcos Jun& Alves, Ana Liz Garcia& Rodrigues, Celso Antonio…[et al.]. 2014. Peritoneal Reactivity Evaluation in Horses Subjected to Experimental Small Colon Enterotomy and Treated with Subcutaneous Heparin. Veterinary Medicine International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1051912
Modern Language Association (MLA)
Alonso, Juliana de Moura…[et al.]. Peritoneal Reactivity Evaluation in Horses Subjected to Experimental Small Colon Enterotomy and Treated with Subcutaneous Heparin. Veterinary Medicine International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1051912
American Medical Association (AMA)
Alonso, Juliana de Moura& Rodrigues, Karoline Alves& Yamada, Ana Lúcia Miluzzi& Watanabe, Marcos Jun& Alves, Ana Liz Garcia& Rodrigues, Celso Antonio…[et al.]. Peritoneal Reactivity Evaluation in Horses Subjected to Experimental Small Colon Enterotomy and Treated with Subcutaneous Heparin. Veterinary Medicine International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1051912
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1051912