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Retrospective and Prospective Investigations about “Quatrefoil” Erythrocytes in Canine Blood Smears
Joint Authors
Bernabò, Nicola
Lubas, George
Gavazza, Alessandra
Ricci, Marianna
Brettoni, Martina
Gugliucci, Biancaurora
Pasquini, Anna
Rispoli, Daniela
Source
Veterinary Medicine International
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-06
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The presence of unusual two RBCs patterns (so-called “quatrefoil RBCs,” qRBCs) on canine blood smears at Optical Microscope (OM) was seen during routine evaluation of CBCs.
Two consecutive retrospective investigations were arranged including about 7,000 CBCs and clinical records and laboratory data from dogs showing qRBCs.
Few samples with qRBCs were prepared for Scanning Electron Microscope (SEM).
qRBCs were found in 6.89% (139 of 2016) and 8.47% (133 of 1569) of dogs and in 3.89% (154 of 3,958) and 4.47% (138 of 3,081) of CBCs (some dogs were tested more than once).
Statistical analysis was significant for age groups (Chi squared, P < 0.0001 ), decreased total leukocyte and neutrophil counts (ANOVA, P < 0.0001 ), RBCs anisocytosis, polychromasia, and Howell-Jolly bodies (ANOVA, P < 0.018 , <0.005, and <0.003, respectively).
qRBCs were distributed in the area of feathered edge and at the smear side of body-feathered edge area in blood films.
SEM ruled out the possibility of an optical illusion or an accidental overlap.
qRBCs are associated with ageing of dogs, total leukocyte and neutrophil counts, and RBC anisocytosis, polychromasia, and Howell-Jolly bodies.
Few hypotheses were discussed to explain the origin and meaning of this RBC arrangement.
American Psychological Association (APA)
Gavazza, Alessandra& Ricci, Marianna& Brettoni, Martina& Gugliucci, Biancaurora& Pasquini, Anna& Rispoli, Daniela…[et al.]. 2014. Retrospective and Prospective Investigations about “Quatrefoil” Erythrocytes in Canine Blood Smears. Veterinary Medicine International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1051917
Modern Language Association (MLA)
Gavazza, Alessandra…[et al.]. Retrospective and Prospective Investigations about “Quatrefoil” Erythrocytes in Canine Blood Smears. Veterinary Medicine International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-1051917
American Medical Association (AMA)
Gavazza, Alessandra& Ricci, Marianna& Brettoni, Martina& Gugliucci, Biancaurora& Pasquini, Anna& Rispoli, Daniela…[et al.]. Retrospective and Prospective Investigations about “Quatrefoil” Erythrocytes in Canine Blood Smears. Veterinary Medicine International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1051917
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1051917