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Temporal Bacteriostatic Effect and Growth Factor Loss in Equine Platelet Components and Plasma Cultured with Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus: A Comparative In Vitro Study
Joint Authors
Carmona, J. U.
López, Catalina
Álvarez, María E.
Source
Veterinary Medicine International
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-24
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The aims were (1) to evaluate the bacteriostatic effect of platelet-rich plasma (PRP), platelet-rich gel (PRG), leukocyte-poor plasma (LPP), leukocyte-poor gel (LPG), plasma, and heat-inactivated plasma (IP) on both methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA) over a period of 24 h; (2) to determine and to compare the concentrations and degradation over time of platelet factor 4 (PF-4), transforming growth factor beta 1 (TGF-β1), and platelet-derived growth factor isoform BB (PDGF-BB); and (3) to identify any correlations between MSSA and MRSA growth and either the cellular, PF-4, TGF-β1, or PDGF-BB concentrations in the blood components.
PRP and its byproducts from 18 horses were obtained by the tube method.
All blood components were cultured with either MSSA or MRSA.
Bacterial growth, PF-4, TGF-β1, and PDGF-BB were determined at 6 h and 24 h.
At six hours, bacterial growth was significantly inhibited by all blood components, with the exception of IP.
MSSA was more sensitive to the treatments than MRSA.
At 24 hours, bacterial growth was significantly higher in IP.
MRSA bacterial growth was significantly higher in PRP, LPP, and plasma when compared to MSSA.
Growth factor concentrations were not significantly affected by bacteria.
American Psychological Association (APA)
López, Catalina& Álvarez, María E.& Carmona, J. U.. 2014. Temporal Bacteriostatic Effect and Growth Factor Loss in Equine Platelet Components and Plasma Cultured with Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus: A Comparative In Vitro Study. Veterinary Medicine International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1051929
Modern Language Association (MLA)
López, Catalina…[et al.]. Temporal Bacteriostatic Effect and Growth Factor Loss in Equine Platelet Components and Plasma Cultured with Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus: A Comparative In Vitro Study. Veterinary Medicine International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1051929
American Medical Association (AMA)
López, Catalina& Álvarez, María E.& Carmona, J. U.. Temporal Bacteriostatic Effect and Growth Factor Loss in Equine Platelet Components and Plasma Cultured with Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus: A Comparative In Vitro Study. Veterinary Medicine International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1051929
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1051929