The Chemistry of Bioconjugation in Nanoparticles-Based Drug Delivery System
Joint Authors
Werengowska-Ciećwierz, Karolina
Wiśniewski, Marek
Terzyk, Artur P.
Furmaniak, Sylwester
Source
Advances in Condensed Matter Physics
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-27, 27 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-28
Country of Publication
Egypt
No. of Pages
27
Main Subjects
Abstract EN
Nanomedicine is, generally, the application of nanotechnology to medicine.
The term nanomedicine includes monitoring, construction of novel drug delivery systems, and any possible future applications of nanotechnology and nanovaccinology.
In this review, the most important ligand-nanocarrier and drug-nanocarrier bioconjugations are described.
The detailed characterizations of covalently formed bonds between targeted ligand and nanocarrier, including amide, thioether, disulfide, acetyl-hydrazone and polycyclic groups, are described.
Also, the coupling of small elements and heteroatoms in the form of R-X-R the “click chemistry” groups is shown.
Physical adsorption and chemical bonding of drug to nanocarrier surface involving drug on the internal or external surfaces of nanocarriers are described throughout possibility of the formation of the above-mentioned functionalities.
Moreover, the most popular nanostructures (liposomes, micelles, polymeric nanoparticles, dendrimers, carbon nanotubes, and nanohorns) are characterized as nanocarriers.
Building of modern drug carrier is a new method which could be effectively applied in targeted anticancer therapy.
American Psychological Association (APA)
Werengowska-Ciećwierz, Karolina& Wiśniewski, Marek& Terzyk, Artur P.& Furmaniak, Sylwester. 2015. The Chemistry of Bioconjugation in Nanoparticles-Based Drug Delivery System. Advances in Condensed Matter Physics،Vol. 2015, no. 2015, pp.1-27.
https://search.emarefa.net/detail/BIM-1052233
Modern Language Association (MLA)
Werengowska-Ciećwierz, Karolina…[et al.]. The Chemistry of Bioconjugation in Nanoparticles-Based Drug Delivery System. Advances in Condensed Matter Physics No. 2015 (2015), pp.1-27.
https://search.emarefa.net/detail/BIM-1052233
American Medical Association (AMA)
Werengowska-Ciećwierz, Karolina& Wiśniewski, Marek& Terzyk, Artur P.& Furmaniak, Sylwester. The Chemistry of Bioconjugation in Nanoparticles-Based Drug Delivery System. Advances in Condensed Matter Physics. 2015. Vol. 2015, no. 2015, pp.1-27.
https://search.emarefa.net/detail/BIM-1052233
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1052233