Significance of Circulating Tumor Cells in Soft Tissue Sarcoma
Joint Authors
Nicolazzo, Chiara
Gradilone, Angela
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-18
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Circulating tumor cells can be detected from the peripheral blood of cancer patients.
Their prognostic value has been established in the last 10 years for metastatic colorectal, breast, and prostate cancer.
On the contrary their presence in patients affected by sarcomas has been poorly investigated.
The discovery of EpCAM mRNA expression in different sarcoma cell lines and in a small cohort of metastatic sarcoma patients supports further investigations on these rare tumors to deepen the importance of CTC isolation.
Although it is not clear whether EpCAM expression might be originally present on tumor sarcoma cells or acquired during the mesenchymal-epithelial transition, the discovery of EpCAM on circulating sarcoma cells opens a new scenario in CTC detection in patients affected by a rare mesenchymal tumor.
American Psychological Association (APA)
Nicolazzo, Chiara& Gradilone, Angela. 2015. Significance of Circulating Tumor Cells in Soft Tissue Sarcoma. Analytical Cellular Pathology،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1052365
Modern Language Association (MLA)
Nicolazzo, Chiara& Gradilone, Angela. Significance of Circulating Tumor Cells in Soft Tissue Sarcoma. Analytical Cellular Pathology No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1052365
American Medical Association (AMA)
Nicolazzo, Chiara& Gradilone, Angela. Significance of Circulating Tumor Cells in Soft Tissue Sarcoma. Analytical Cellular Pathology. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1052365
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1052365