The Iron Status of Sickle Cell Anaemia Patients in Ilorin, North Central Nigeria
Joint Authors
Sani, Musa A.
Adewuyi, James O.
Olawumi, Hannah O.
Shittu, Rasaki O.
Babatunde, A. S.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-15
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objectives.
Sickle cell anaemia (SCA) is one of the commonest genetic disorders in the world.
It is characterized by anaemia, periodic attacks of thrombotic pain, and chronic systemic organ damage.
Recent studies have suggested that individuals with SCA especially from developing countries are more likely to be iron deficient rather than have iron overload.
The study aims to determine the iron status of SCA patients in Ilorin, Nigeria.
Methods.
A cross-sectional study of 45 SCA patients in steady state and 45 non-SCA controls was undertaken.
FBC, blood film, sFC, sTfR, and sTfR/log sFC index were done on all subjects.
Results.
The mean patients’ serum ferritin (589.33 ± 427.61 ng/mL) was significantly higher than the mean serum ferritin of the controls (184.53 ± 119.74 ng/mL).
The mean serum transferrin receptor of the patients (4.24 ± 0.17 μg/mL) was higher than that of the controls (3.96 ± 0.17 μg/mL) (p=0.290).
The mean serum transferrin receptor (sTfR)/log serum ferritin index of the patients (1.65 ± 0.27 μg/mL) was significantly lower than that of the control (1.82 ± 0.18 μg/mL) (p=0.031).
Conclusion.
Iron deficiency is uncommon in SCA patients and periodic monitoring of the haematological, biochemical, and clinical features for iron status in SCA patients is advised.
American Psychological Association (APA)
Sani, Musa A.& Adewuyi, James O.& Babatunde, A. S.& Olawumi, Hannah O.& Shittu, Rasaki O.. 2015. The Iron Status of Sickle Cell Anaemia Patients in Ilorin, North Central Nigeria. Advances in Hematology،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1052439
Modern Language Association (MLA)
Sani, Musa A.…[et al.]. The Iron Status of Sickle Cell Anaemia Patients in Ilorin, North Central Nigeria. Advances in Hematology No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1052439
American Medical Association (AMA)
Sani, Musa A.& Adewuyi, James O.& Babatunde, A. S.& Olawumi, Hannah O.& Shittu, Rasaki O.. The Iron Status of Sickle Cell Anaemia Patients in Ilorin, North Central Nigeria. Advances in Hematology. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1052439
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1052439