Predictors of Outcome and Severity in Adult Filipino Patients with Febrile Neutropenia
Joint Authors
Yu, Marc Gregory Y.
Villalobos, Ralph Elvi M.
Juan-Bartolome, Ma. Jasmin Marinela C.
Berba, Regina P.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Aim.
The study aimed to describe the profile of Filipino febrile neutropenia patients and to determine parameters associated with severe outcomes.
Methods.
This is a retrospective study of Filipino febrile neutropenia patients admitted to the Philippine General Hospital.
Patients were described in terms of clinical presentation and stratified according to the presence or absence of severe outcomes.
Prognostic factors were then identified using regression analysis.
Results.
115 febrile episodes in 102 patients were identified.
Regression analysis yielded prolonged fever >7 days prior to admission (OR 2.43; 95% CI, 0.77–7.74), isolation of a pathogen on cultures (OR 2.69; 95% CI, 1.04–6.98), and nadir absolute neutrophil count (ANC) < 100 during admission (OR 1.96; 95% CI, 0.75–5.12) as significant predictors of poor outcome.
Factors that significantly correlated with better outcome were granulocyte colony-stimulating factor (G-CSF) use (OR 0.31; 95% CI, 0.11–0.85) and completeness of antibiotic therapy (OR 0.26; 95% CI, 0.10–0.67).
Conclusion.
Prolonged fever >7 days prior to admission, positive pathogen on cultures, and nadir ANC < 100 during admission predicted severe outcomes, whereas G-CSF use and complete antibiotic therapy were associated with better outcomes.
These prognostic variables might be useful in identifying patients that need more intensive treatment and monitoring.
American Psychological Association (APA)
Yu, Marc Gregory Y.& Villalobos, Ralph Elvi M.& Juan-Bartolome, Ma. Jasmin Marinela C.& Berba, Regina P.. 2015. Predictors of Outcome and Severity in Adult Filipino Patients with Febrile Neutropenia. Advances in Hematology،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1052451
Modern Language Association (MLA)
Yu, Marc Gregory Y.…[et al.]. Predictors of Outcome and Severity in Adult Filipino Patients with Febrile Neutropenia. Advances in Hematology No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1052451
American Medical Association (AMA)
Yu, Marc Gregory Y.& Villalobos, Ralph Elvi M.& Juan-Bartolome, Ma. Jasmin Marinela C.& Berba, Regina P.. Predictors of Outcome and Severity in Adult Filipino Patients with Febrile Neutropenia. Advances in Hematology. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1052451
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1052451