A Turbidity Test Based Centrifugal Microfluidics Diagnostic System for Simultaneous Detection of HBV, HCV, and CMV

Abstract EN

This paper presents a LAMP- (loop-mediated isothermal amplification-) based lab-on-disk optical system that allows the simultaneous detection of hepatitis B virus, hepatitis C virus, and cytomegalovirus.

The various flow stages are controlled in the proposed system using different balance among centrifugal pumping, Coriolis pumping, and the capillary force.

We have implemented a servo system for positioning and speed control for the heating and centrifugal pumping.

We have also successfully employed a polymer light-emitting diode section for turbidity detection.

The easy-to-use one-click system can perform diagnostics in less than 1 hour.