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Fullerenol-Capped Porous Silica Nanoparticles for pH-Responsive Drug Delivery
Joint Authors
Knežević, Nikola Ž.
Milenković, Sanja
Jović, Danica
Lazarevic, Slavica
Mrdjanović, Jasminka
Djordjevic, Aleksandar
Source
Advances in Materials Science and Engineering
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-21
Country of Publication
Egypt
No. of Pages
6
Abstract EN
Novel nanocomposite containing fullerenol nanoparticles (FNP) and porous silica nanoparticles (PSNs) was constructed and characterized.
The capability of FNP to serve as a pore-capping agent and for entrapping 9-aminoacridine (9-AA) inside the pores of the PSN material was also demonstrated.
Nitrogen sorption measurements evidence the successful capping of the silica pores while thermogravimetric analysis of FNP loaded PSN indicates the existence of pore-loaded fullerenol molecules.
Higher amount of the drug release was noted by exposing the material to weakly acidic conditions in comparison to physiological pH, which may find application in targeted treatment of weakly acidic tumor tissues.
American Psychological Association (APA)
Knežević, Nikola Ž.& Milenković, Sanja& Jović, Danica& Lazarevic, Slavica& Mrdjanović, Jasminka& Djordjevic, Aleksandar. 2015. Fullerenol-Capped Porous Silica Nanoparticles for pH-Responsive Drug Delivery. Advances in Materials Science and Engineering،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1053350
Modern Language Association (MLA)
Knežević, Nikola Ž.…[et al.]. Fullerenol-Capped Porous Silica Nanoparticles for pH-Responsive Drug Delivery. Advances in Materials Science and Engineering No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1053350
American Medical Association (AMA)
Knežević, Nikola Ž.& Milenković, Sanja& Jović, Danica& Lazarevic, Slavica& Mrdjanović, Jasminka& Djordjevic, Aleksandar. Fullerenol-Capped Porous Silica Nanoparticles for pH-Responsive Drug Delivery. Advances in Materials Science and Engineering. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1053350
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1053350