Melatonin and Ischemic Stroke: Mechanistic Roles and Action
Joint Authors
Andrabi, Syed Suhail
Tabassum, Heena
Parvez, Suhel
Source
Advances in Pharmacological and Pharmaceutical Sciences
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-07
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Stroke is one of the most devastating neurological disabilities and brain’s vulnerability towards it proves to be fatal and socio-economic loss of millions of people worldwide.
Ischemic stroke remains at the center stage of it, because of its prevalence amongst the several other types attacking the brain.
The various cascades of events that have been associated with stroke involve oxidative stress, excitotoxicity, mitochondrial dysfunction, upregulation of Ca2+ level, and so forth.
Melatonin is a neurohormone secreted by pineal and extra pineal tissues responsible for various physiological processes like sleep and mood behaviour.
Melatonin has been implicated in various neurological diseases because of its antioxidative, antiapoptotic, and anti-inflammatory properties.
We have previously reviewed the neuroprotective effect of melatonin in various models of brain injury like traumatic brain injury and spinal cord injury.
In this review, we have put together the various causes and consequence of stroke and protective role of melatonin in ischemic stroke.
American Psychological Association (APA)
Andrabi, Syed Suhail& Parvez, Suhel& Tabassum, Heena. 2015. Melatonin and Ischemic Stroke: Mechanistic Roles and Action. Advances in Pharmacological and Pharmaceutical Sciences،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1053903
Modern Language Association (MLA)
Andrabi, Syed Suhail…[et al.]. Melatonin and Ischemic Stroke: Mechanistic Roles and Action. Advances in Pharmacological and Pharmaceutical Sciences No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1053903
American Medical Association (AMA)
Andrabi, Syed Suhail& Parvez, Suhel& Tabassum, Heena. Melatonin and Ischemic Stroke: Mechanistic Roles and Action. Advances in Pharmacological and Pharmaceutical Sciences. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1053903
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1053903