Assessment of the Carbon Monoxide Metabolism of the Hyperthermophilic Sulfate-Reducing Archaeon Archaeoglobus fulgidus VC-16 by Comparative Transcriptome Analyses
Joint Authors
Hocking, William P.
Roalkvam, Irene
Magnussen, Carina
Stokke, Runar
Steen, Ida H.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-06
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
The hyperthermophilic, sulfate-reducing archaeon, Archaeoglobus fulgidus, utilizes CO as an energy source and it is resistant to the toxic effects of high CO concentrations.
Herein, transcription profiles were obtained from A.
fulgidus during growth with CO and sulfate or thiosulfate, or without an electron acceptor.
This provided a basis for a model of the CO metabolism of A.
fulgidus.
The model suggests proton translocation by “Mitchell-type” loops facilitated by Fqo catalyzing a Fd red :menaquinone oxidoreductase reaction, as the major mode of energy conservation, rather than formate or H2 cycling during respiratory growth.
The bifunctional CODH (cdhAB-2) is predicted to play an ubiquitous role in the metabolism of CO, and a novel nitrate reductase-associated respiratory complex was induced specifically in the presence of sulfate.
A potential role of this complex in relation to Fd red and APS reduction is discussed.
Multiple membrane-bound heterodisulfide reductase (DsrMK) could promote both energy-conserving and non-energy-conserving menaquinol oxidation.
Finally, the FqoF subunit may catalyze a Fd red :F420 oxidoreductase reaction.
In the absence of electron acceptor, downregulation of F420H2 dependent steps of the acetyl-CoA pathway is linked to transient formate generation.
Overall, carboxidotrophic growth seems as an intrinsic capacity of A.
fulgidus with little need for novel resistance or respiratory complexes.
American Psychological Association (APA)
Hocking, William P.& Roalkvam, Irene& Magnussen, Carina& Stokke, Runar& Steen, Ida H.. 2015. Assessment of the Carbon Monoxide Metabolism of the Hyperthermophilic Sulfate-Reducing Archaeon Archaeoglobus fulgidus VC-16 by Comparative Transcriptome Analyses. Archaea،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1053921
Modern Language Association (MLA)
Hocking, William P.…[et al.]. Assessment of the Carbon Monoxide Metabolism of the Hyperthermophilic Sulfate-Reducing Archaeon Archaeoglobus fulgidus VC-16 by Comparative Transcriptome Analyses. Archaea No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1053921
American Medical Association (AMA)
Hocking, William P.& Roalkvam, Irene& Magnussen, Carina& Stokke, Runar& Steen, Ida H.. Assessment of the Carbon Monoxide Metabolism of the Hyperthermophilic Sulfate-Reducing Archaeon Archaeoglobus fulgidus VC-16 by Comparative Transcriptome Analyses. Archaea. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1053921
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1053921