Characterization of Fatty Acids in Crenarchaeota by GC-MS and NMR
Joint Authors
Hamerly, Timothy
Tripet, Brian
Wurch, Louie
Hettich, Robert L.
Podar, Mircea
Bothner, Brian
Copié, Valérie
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-31
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Lipids composed of condensed isoprenyl units connected to glycerol backbones by ether linkages are a distinguishing feature of Archaea.
Data suggesting that fatty acids with linear hydrocarbon chains are present in some Archaea have been available for decades.
However, lack of genomic and biochemical evidence for the metabolic machinery required to synthesize and degrade fatty acids has left the field unclear on this potentially significant biochemical aspect.
Because lipids are energy currency and cell signaling molecules, their presence in Archaea is significant for understanding archaeal biology.
A recent large-scale bioinformatics analysis reignited the debate as to the importance of fatty acids in Archaea by presenting genetic evidence for the presence of enzymes required for anabolic and catabolic fatty acid metabolism across the archaeal domain.
Here, we present direct biochemical evidence from gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) spectroscopy for the presence of fatty acids in two members of the Crenarchaeota, Sulfolobus solfataricus and Ignicoccus hospitalis.
This is the first report providing biochemical data for the existence of fatty acids in these Crenarchaeota, opening new discussions on energy balance and the potential for the discovery of new thermostable enzymes for industry.
American Psychological Association (APA)
Hamerly, Timothy& Tripet, Brian& Wurch, Louie& Hettich, Robert L.& Podar, Mircea& Bothner, Brian…[et al.]. 2015. Characterization of Fatty Acids in Crenarchaeota by GC-MS and NMR. Archaea،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1053927
Modern Language Association (MLA)
Hamerly, Timothy…[et al.]. Characterization of Fatty Acids in Crenarchaeota by GC-MS and NMR. Archaea No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1053927
American Medical Association (AMA)
Hamerly, Timothy& Tripet, Brian& Wurch, Louie& Hettich, Robert L.& Podar, Mircea& Bothner, Brian…[et al.]. Characterization of Fatty Acids in Crenarchaeota by GC-MS and NMR. Archaea. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1053927
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1053927