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Prevalence of and Risk Factors for Lipoatrophy in Patients with HIV Infection in Nigeria
Joint Authors
Iwuala, Sandra Omozehio
Sabir, Anas A.
Olamoyegun, Michael Adeyemi
Okany, Charles C.
Lesi, Olufunmilayo A.
Fasanmade, Olufemi
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-02
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Although the association between lipoatrophy and highly active antiretroviral therapy (HAART) is well known, other nondrug factors may be associated with lipoatrophy in people living with HIV/AIDS (PLWHA).
There are no reports of lipoatrophy from Nigeria, a country with the second largest number of PLWHA.
We aimed to determine the prevalence, characteristics, and factors associated with lipoatrophy in a cohort of patients attending the HIV clinic in Lagos University Teaching Hospital, Nigeria.
Methods.
Two hundred and eighty-eight patients with HIV infection were recruited for the study.
The study protocol involved administration of a questionnaire, targeted physical examination (including anthropometric indices and skin fold thickness), and bioelectrical impedance analysis measurements.
Lipoatrophy was defined clinically.
Results.
Lipoatrophy was present in 75 (26.0%) persons.
It was associated with lower body circumferences, skin fold thicknesses, and lower % body fat with preservation of skeletal muscle mass (all P<0.05).
Male gender and HAART use were the factors associated with lipoatrophy on multivariate analysis (P<0.05).
Conclusion.
Lipoatrophy is frequently encountered in patients with HIV infection in Nigeria, with HAART use conferring an added factor in its development.
There is need for more physician and patient awareness of this condition.
American Psychological Association (APA)
Iwuala, Sandra Omozehio& Lesi, Olufunmilayo A.& Fasanmade, Olufemi& Sabir, Anas A.& Olamoyegun, Michael Adeyemi& Okany, Charles C.. 2015. Prevalence of and Risk Factors for Lipoatrophy in Patients with HIV Infection in Nigeria. AIDS Research and Treatment،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1053961
Modern Language Association (MLA)
Iwuala, Sandra Omozehio…[et al.]. Prevalence of and Risk Factors for Lipoatrophy in Patients with HIV Infection in Nigeria. AIDS Research and Treatment No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1053961
American Medical Association (AMA)
Iwuala, Sandra Omozehio& Lesi, Olufunmilayo A.& Fasanmade, Olufemi& Sabir, Anas A.& Olamoyegun, Michael Adeyemi& Okany, Charles C.. Prevalence of and Risk Factors for Lipoatrophy in Patients with HIV Infection in Nigeria. AIDS Research and Treatment. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1053961
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1053961