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Fructosamine and Hemoglobin A1c Correlations in HIV-Infected Adults in Routine Clinical Care: Impact of Anemia and Albumin Levels
Joint Authors
Duran, Luisa
Rodriguez, Carla
Drozd, Dan
Nance, Robin M.
Delaney, J. A. Chris
Burkholder, Greer
Mugavero, Michael J.
Willig, James H.
Warriner, Amy H.
Crane, Paul K.
Atkinson, Ben E.
Harrington, Robert D.
Dhanireddy, Shireesha
Kitahata, Mari M.
Crane, Heidi M.
Saag, Michael
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Fructosamine is an alternative method to hemoglobin A1c (HbA1c) for determining average glycemia.
However, its use has not been extensively evaluated in persons living with HIV (PLWH).
We examined the relationship between HbA1c and fructosamine values, specifically focusing on anemia (which can affect HbA1c) and albumin as a marker of liver disease.
We included 345 PLWH from two sites.
We examined Spearman rank correlations between fructosamine and HbA1c and performed linear test for trends to compare fructosamine and HbA1c correlations by hemoglobin and albumin quartiles.
We examined discrepant individuals with values elevated only on one test.
We found a correlation of 0.70 between fructosamine and HbA1c levels.
Trend tests for correlations between fructosamine and HbA1c were significant for both albumin (p=0.05) and hemoglobin (p=0.01) with the lowest correlations in the lowest hemoglobin quartile.
We identified participants with unremarkable HbA1c values but elevated fructosamine values.
These discrepant individuals had lower mean hemoglobin levels than those elevated by both tests.
We demonstrated a large correlation between HbA1c and fructosamine across a range of hemoglobin and albumin levels.
There were discrepant cases particularly among those with lower hemoglobin levels.
Future studies are needed to clarify the use of fructosamine for diabetes management in PWLH.
American Psychological Association (APA)
Duran, Luisa& Rodriguez, Carla& Drozd, Dan& Nance, Robin M.& Delaney, J. A. Chris& Burkholder, Greer…[et al.]. 2015. Fructosamine and Hemoglobin A1c Correlations in HIV-Infected Adults in Routine Clinical Care: Impact of Anemia and Albumin Levels. AIDS Research and Treatment،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1053963
Modern Language Association (MLA)
Duran, Luisa…[et al.]. Fructosamine and Hemoglobin A1c Correlations in HIV-Infected Adults in Routine Clinical Care: Impact of Anemia and Albumin Levels. AIDS Research and Treatment No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1053963
American Medical Association (AMA)
Duran, Luisa& Rodriguez, Carla& Drozd, Dan& Nance, Robin M.& Delaney, J. A. Chris& Burkholder, Greer…[et al.]. Fructosamine and Hemoglobin A1c Correlations in HIV-Infected Adults in Routine Clinical Care: Impact of Anemia and Albumin Levels. AIDS Research and Treatment. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1053963
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1053963