Seroprevalence of Herpes Simplex Virus Infection in HIV Coinfected Individuals in Eastern India with Risk Factor Analysis
Joint Authors
Debprasad, Chattopadhyay
Nag, Soumyabrata
Sarkar, Soma
Bhattacharya, Sanjoy
Biswas, Rahul
SenGupta, Manideepa
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Herpes simplex virus type 2 (HSV-2) is the cause of most genital herpes while HSV-1 is responsible for orolabial and facial lesions.
In immunocompromised individuals, like HIV patients, impaired immunity leads to more frequent symptomatic and asymptomatic HSV infection.
Fifty-two blood samples from HIV patients with clinically diagnosed HSV infection were taken as cases, while 45 blood samples each from HIV-infected (HIV control) and noninfected patients without any herpetic lesion (non-HIV control) were taken as control.
Serum was tested for IgM and IgG antibodies of both HSV-1 and HSV-2 by ELISA.
The seroprevalence was compared among the three groups of study population, considering the demographic and socioeconomic parameters.
The HSV-2 IgM was significantly higher (p<0.005) in the HIV patient group (34.6%) than the HIV control (2.2%) and non-HIV control (2.2%) groups, whereas HSV-2 IgG seroprevalence was higher in both HIV patient (61.5%) and HIV control (57.8%) groups than the non-HIV control group (17.8%).
The prevalence of HSV-2 was significantly higher in persons with multiple partners and in the reproductive age group.
The overall seroprevalence of HSV-1 IgM was too low (<5%), whereas it was too high (about 90%) with HSV-1 IgG in all three study groups.
American Psychological Association (APA)
Nag, Soumyabrata& Sarkar, Soma& Debprasad, Chattopadhyay& Bhattacharya, Sanjoy& Biswas, Rahul& SenGupta, Manideepa. 2015. Seroprevalence of Herpes Simplex Virus Infection in HIV Coinfected Individuals in Eastern India with Risk Factor Analysis. Advances in Virology،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1054027
Modern Language Association (MLA)
Nag, Soumyabrata…[et al.]. Seroprevalence of Herpes Simplex Virus Infection in HIV Coinfected Individuals in Eastern India with Risk Factor Analysis. Advances in Virology No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1054027
American Medical Association (AMA)
Nag, Soumyabrata& Sarkar, Soma& Debprasad, Chattopadhyay& Bhattacharya, Sanjoy& Biswas, Rahul& SenGupta, Manideepa. Seroprevalence of Herpes Simplex Virus Infection in HIV Coinfected Individuals in Eastern India with Risk Factor Analysis. Advances in Virology. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1054027
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054027