SALMO and S3M: A Saliva Model and a Single Saliva Salt Model for Equilibrium Studies
Joint Authors
Sammartano, Silvio
Milea, Demetrio
Pettignano, Alberto
Crea, Francesco
De Stefano, Concetta
Source
Bioinorganic Chemistry and Applications
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-04
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
A model of synthetic saliva (SALMO, SALiva MOdel) is proposed for its use as standard medium in in vitro equilibrium and speciation studies of real saliva.
The concentrations come out from the literature analysis of the composition of both real saliva and synthetic saliva.
The chief interactions of main inorganic components of saliva, as well as urea and amino acids, are taken into account on the basis of a complex formation model, which also considers the dependence of the stability constants of these species on ionic strength and temperature.
These last features allow the modelling of the speciation of saliva in different physiological conditions deriving from processes like dilution, pH, and temperature changes.
To simplify equilibrium calculations, a plain approach is also proposed, in order to take into account all the interactions among the major components of saliva, by considering the inorganic components of saliva as a single 1 : 1 salt (MX), whose concentration is c MX = ( 1 / 2 ) ∑ c i ( c i = analytical concentration of all the ions) and z ion charge calculated as z=±( I / c MX ) 1 / 2 = ±1.163.
The use of the Single Saliva Salt Model (S3M) considerably reduces the complexity of the systems to be investigated.
In fact, only four species deriving from internal ionic medium interactions must be considered.
American Psychological Association (APA)
Crea, Francesco& De Stefano, Concetta& Milea, Demetrio& Pettignano, Alberto& Sammartano, Silvio. 2015. SALMO and S3M: A Saliva Model and a Single Saliva Salt Model for Equilibrium Studies. Bioinorganic Chemistry and Applications،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1054043
Modern Language Association (MLA)
Crea, Francesco…[et al.]. SALMO and S3M: A Saliva Model and a Single Saliva Salt Model for Equilibrium Studies. Bioinorganic Chemistry and Applications No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1054043
American Medical Association (AMA)
Crea, Francesco& De Stefano, Concetta& Milea, Demetrio& Pettignano, Alberto& Sammartano, Silvio. SALMO and S3M: A Saliva Model and a Single Saliva Salt Model for Equilibrium Studies. Bioinorganic Chemistry and Applications. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1054043
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054043