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Stability Constants of Mixed Ligand Complexes of Nickel(II) with Adenine and Some Amino Acids
Author
Source
Bioinorganic Chemistry and Applications
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-30
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Nickel is one of the essential trace elements found in biological systems.
It is mostly found in nickel-based enzymes as an essential cofactor.
It forms coordination complexes with amino acids within enzymes.
Nickel is also present in nucleic acids, though its function in DNA or RNA is still not clearly understood.
In this study, complex formation tendencies of Ni(II) with adenine and certain L-amino acids such as aspartic acid, glutamic acid, asparagine, leucine, phenylalanine, and tryptophan were investigated in an aqueous medium.
Potentiometric equilibrium measurements showed that both binary and ternary complexes of Ni(II) form with adenine and the above-mentioned L-amino acids.
Ternary complexes of Ni(II)-adenine-L-amino acids are formed by stepwise mechanisms.
Relative stabilities of the ternary complexes are compared with those of the corresponding binary complexes in terms of Δlog10K, log10X, and % RS values.
It was shown that the most stable ternary complex is Ni(II):Ade:L-Asn while the weakest one is Ni(II):Ade:L-Phe in aqueous solution used in this research.
In addition, results of this research clearly show that various binary and ternary type Ni(II) complexes are formed in different concentrations as a function of pH in aqueous solution.
American Psychological Association (APA)
Türkel, Naciye. 2015. Stability Constants of Mixed Ligand Complexes of Nickel(II) with Adenine and Some Amino Acids. Bioinorganic Chemistry and Applications،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1054044
Modern Language Association (MLA)
Türkel, Naciye. Stability Constants of Mixed Ligand Complexes of Nickel(II) with Adenine and Some Amino Acids. Bioinorganic Chemistry and Applications No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1054044
American Medical Association (AMA)
Türkel, Naciye. Stability Constants of Mixed Ligand Complexes of Nickel(II) with Adenine and Some Amino Acids. Bioinorganic Chemistry and Applications. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1054044
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054044