Novel Synthesis Method of Micronized Ti-Zeolite Na-A and Cytotoxic Activity of Its Silver Exchanged Form

Joint Authors

Youssef, H. F.
Abo-almaged, H. H.
El-Bassyouni, G. T.
Hegazy, W. H.

Source

Bioinorganic Chemistry and Applications

Issue

Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2015-02-03

Country of Publication

Egypt

No. of Pages

12

Main Subjects

Biology

Abstract EN

The core-shell method is used as a novel synthetic process of micronized Ti-Zeolite Na-A which involves calcination at 700°C of coated Egyptian Kaolin with titanium tetrachloride in acidic medium as the first step.

The produced Ti-coated metakaolinite is subjected to microwave irradiation at low temperature of 80°C for 2 h.

The prepared micronized Ti-containing Zeolites-A (Ti-Z-A) is characterized by FTIR, XRF, XRD, SEM, and EDS elemental analysis.

Ag-exchanged form of Ti-Z-Ag is also prepared and characterized.

The Wt% of silver exchanged onto the Ti-Zeolite structure was determined by atomic absorption spectra.

The in vitro cytotoxic activity of Ti-Z-Ag against human hepatocellular carcinoma cell line (HePG2), colon cell line carcinoma (HCT116), lung carcinoma cell line (A549), and human Caucasian breast adenocarcinoma (MCF7) is reported.

The results were promising and revealed that the exchanged Ag form of micronized Ti-Zeolite-A can be used as novel antitumor drug.

American Psychological Association (APA)

Youssef, H. F.& Hegazy, W. H.& Abo-almaged, H. H.& El-Bassyouni, G. T.. 2015. Novel Synthesis Method of Micronized Ti-Zeolite Na-A and Cytotoxic Activity of Its Silver Exchanged Form. Bioinorganic Chemistry and Applications،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1054048

Modern Language Association (MLA)

Youssef, H. F.…[et al.]. Novel Synthesis Method of Micronized Ti-Zeolite Na-A and Cytotoxic Activity of Its Silver Exchanged Form. Bioinorganic Chemistry and Applications No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1054048

American Medical Association (AMA)

Youssef, H. F.& Hegazy, W. H.& Abo-almaged, H. H.& El-Bassyouni, G. T.. Novel Synthesis Method of Micronized Ti-Zeolite Na-A and Cytotoxic Activity of Its Silver Exchanged Form. Bioinorganic Chemistry and Applications. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1054048

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1054048