Highly Flexible Silicone Coated Neural Array for Intracochlear Electrical Stimulation
Joint Authors
Bhatti, P.
Van Beek-King, J.
Sharpe, A.
Crawford, J.
Tridandapani, S.
McKinnon, B.
Blake, D.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-05
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
We present an effective method for tailoring the flexibility of a commercial thin-film polymer electrode array for intracochlear electrical stimulation.
Using a pneumatically driven dispensing system, an average 232±64 μm (mean ± SD) thickness layer of silicone adhesive coating was applied to stiffen the underside of polyimide multisite arrays.
Additional silicone was applied to the tip to protect neural tissue during insertion and along the array to improve surgical handling.
Each array supported 20 platinum sites (180 μm dia., 250 μm pitch), spanning nearly 28 mm in length and 400 μm in width.
We report an average intracochlear stimulating current threshold of 170±93 μA to evoke an auditory brainstem response in 7 acutely deafened felines.
A total of 10 arrays were each inserted through a round window approach into the cochlea’s basal turn of eight felines with one delamination occurring upon insertion (preliminary results of the in vivo data presented at the 48th Annual Meeting American Neurotology Society, Orlando, FL, April 2013, and reported in Van Beek-King 2014).
Using microcomputed tomography imaging (50 μm resolution), distances ranging from 100 to 565 μm from the cochlea’s central modiolus were measured.
Our method combines the utility of readily available commercial devices with a straightforward postprocessing step on the order of 24 hours.
American Psychological Association (APA)
Bhatti, P.& Van Beek-King, J.& Sharpe, A.& Crawford, J.& Tridandapani, S.& McKinnon, B.…[et al.]. 2015. Highly Flexible Silicone Coated Neural Array for Intracochlear Electrical Stimulation. BioMed Research International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1054248
Modern Language Association (MLA)
Bhatti, P.…[et al.]. Highly Flexible Silicone Coated Neural Array for Intracochlear Electrical Stimulation. BioMed Research International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1054248
American Medical Association (AMA)
Bhatti, P.& Van Beek-King, J.& Sharpe, A.& Crawford, J.& Tridandapani, S.& McKinnon, B.…[et al.]. Highly Flexible Silicone Coated Neural Array for Intracochlear Electrical Stimulation. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1054248
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054248