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Increased Postoperative Bleeding Risk among Patients with Local Flap Surgery under Continued Clopidogrel Therapy
Joint Authors
Hanken, Henning
Eichhorn, Wolfgang
Haase, Martina
Kluwe, Lan
Zeuch, Jürgen
Wehrmann, Manfred
Gröbe, Alexander
Smeets, Ralf
Heiland, Max
Birkelbach, Moritz
Rendenbach, Carsten
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-06
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Purpose.
The purpose of the study was to evaluate the influence of a continued antiplatelet therapy with clopidogrel on postoperative bleeding risk in patients undergoing skin tumor resection and reconstruction with local flaps or skin grafts under outpatient conditions.
Patients and Methods.
The authors designed and implemented a retrospective clinical cohort study at the General Hospital Balingen.
The primary endpoint was the bleeding ratio in patients with clopidogrel treatment in comparison to patients without any anticoagulant or antiplatelet therapy.
Wound healing was evaluated on days 1, 3, 5, 7, 10, and 14.
Results.
650 procedures were performed, 123 of them under continued clopidogrel therapy.
There were significantly more postoperative bleeding complications among patients with continued antiplatelet therapy.
Regarding the whole study population, malignant lesions, a larger defect size, and skin grafts were accompanied by a higher rate of bleeding incidents.
However, there were no significant findings in the univariate analysis of the clopidogrel group.
All bleeding incidents were easily manageable.
Conclusion.
Despite an increased bleeding ratio among patients under continued clopidogrel therapy, the performance of simple surgical procedures can be recommended.
However, cautious preparation and careful hemostasis are indispensable.
American Psychological Association (APA)
Eichhorn, Wolfgang& Haase, Martina& Kluwe, Lan& Zeuch, Jürgen& Smeets, Ralf& Hanken, Henning…[et al.]. 2015. Increased Postoperative Bleeding Risk among Patients with Local Flap Surgery under Continued Clopidogrel Therapy. BioMed Research International،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1054253
Modern Language Association (MLA)
Eichhorn, Wolfgang…[et al.]. Increased Postoperative Bleeding Risk among Patients with Local Flap Surgery under Continued Clopidogrel Therapy. BioMed Research International No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1054253
American Medical Association (AMA)
Eichhorn, Wolfgang& Haase, Martina& Kluwe, Lan& Zeuch, Jürgen& Smeets, Ralf& Hanken, Henning…[et al.]. Increased Postoperative Bleeding Risk among Patients with Local Flap Surgery under Continued Clopidogrel Therapy. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1054253
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054253