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Recent Advances on Pathophysiology, Diagnostic and Therapeutic Insights in Cardiac Dysfunction Induced by Antineoplastic Drugs
Joint Authors
Molinaro, Marilisa
Ameri, Pietro
Abete, Pasquale
Di Lisa, Fabio
De Placido, Sabino
Bonaduce, Domenico
Tocchetti, Carlo G.
Petretta, M.
Marone, Gianni
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-25
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Along with the improvement of survival after cancer, cardiotoxicity due to antineoplastic treatments has emerged as a clinically relevant problem.
Potential cardiovascular toxicities due to anticancer agents include QT prolongation and arrhythmias, myocardial ischemia and infarction, hypertension and/or thromboembolism, left ventricular (LV) dysfunction, and heart failure (HF).
The latter is variable in severity, may be reversible or irreversible, and can occur soon after or as a delayed consequence of anticancer treatments.
In the last decade recent advances have emerged in clinical and pathophysiological aspects of LV dysfunction induced by the most widely used anticancer drugs.
In particular, early, sensitive markers of cardiac dysfunction that can predict this form of cardiomyopathy before ejection fraction (EF) is reduced are becoming increasingly important, along with novel therapeutic and cardioprotective strategies, in the attempt of protecting cardiooncologic patients from the development of congestive heart failure.
American Psychological Association (APA)
Molinaro, Marilisa& Ameri, Pietro& Marone, Gianni& Petretta, M.& Abete, Pasquale& Di Lisa, Fabio…[et al.]. 2015. Recent Advances on Pathophysiology, Diagnostic and Therapeutic Insights in Cardiac Dysfunction Induced by Antineoplastic Drugs. BioMed Research International،Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1054332
Modern Language Association (MLA)
Molinaro, Marilisa…[et al.]. Recent Advances on Pathophysiology, Diagnostic and Therapeutic Insights in Cardiac Dysfunction Induced by Antineoplastic Drugs. BioMed Research International No. 2015 (2015), pp.1-14.
https://search.emarefa.net/detail/BIM-1054332
American Medical Association (AMA)
Molinaro, Marilisa& Ameri, Pietro& Marone, Gianni& Petretta, M.& Abete, Pasquale& Di Lisa, Fabio…[et al.]. Recent Advances on Pathophysiology, Diagnostic and Therapeutic Insights in Cardiac Dysfunction Induced by Antineoplastic Drugs. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1054332
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054332