Immunomodulatory Role of Adipose-Derived Stem Cells on Equine Endometriosis
Joint Authors
Ferroni, Letizia
Falomo, Maria Elena
Tocco, Ilaria
Gardin, Chiara
Zavan, Barbara
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-09
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Endometriosis is a degenerative process due to a chronic inflammatory damage leading to extracellular matrix components deposition and glandular fibrosis.
It is known that mesenchymal stem cells secrete a wide range of bioactive molecules, some of them modulating the immune inflammatory response, and others providing regeneration and remodeling of injured tissue.
We have performed in vitro experiments in order to analyze the capability of allogenic equine adipose-derived stem cells (ADSCs) to infiltrate mares’ endometrial tissues and to stimulate the expression of cytokines and metallopeptidases.
Differences in the biologic response to the exposure to ADSCs between pathological and healthy endometrial tissue have been identified.
These results could challenge researchers to progress forward with future studies for the development of a biological therapy with a possible application in translational medicine.
American Psychological Association (APA)
Falomo, Maria Elena& Ferroni, Letizia& Tocco, Ilaria& Gardin, Chiara& Zavan, Barbara. 2015. Immunomodulatory Role of Adipose-Derived Stem Cells on Equine Endometriosis. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1054344
Modern Language Association (MLA)
Falomo, Maria Elena…[et al.]. Immunomodulatory Role of Adipose-Derived Stem Cells on Equine Endometriosis. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1054344
American Medical Association (AMA)
Falomo, Maria Elena& Ferroni, Letizia& Tocco, Ilaria& Gardin, Chiara& Zavan, Barbara. Immunomodulatory Role of Adipose-Derived Stem Cells on Equine Endometriosis. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1054344
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054344