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MR Prediction of Liver Function and Pathology Using Gd-EOB-DTPA: Effect of Liver Volume Consideration
Joint Authors
Shirabe, Ken
Honda, Hiroshi
Shimamoto, Dai
Asayama, Yoshiki
Ushijima, Yasuhiro
Takayama, Yukihisa
Fujita, Nobuhiro
Hida, Tomoyuki
Kubo, Yuichiro
Nishie, Akihiro
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-01
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Purpose.
To evaluate whether the diagnostic performance of Gd-EOB-DTPA-enhanced MRI in evaluating liver function and pathology is improved by considering liver volume (LV).
Methods.
This retrospective study included 104 patients who underwent Gd-EOB-DTPA-enhanced MRI before liver surgery.
For each patient, using the precontrast and hepatobiliary phase images, we calculated the increase rate of the liver-to-spleen signal intensity ratio (LSR), that is, the “ΔLSR,” and the increase rate of the liver-to-muscle signal intensity ratio (LMR), that is, the “ΔLMR.” ΔLSR × LV and ΔLMR × LV were also calculated.
The correlation of each MR parameter with liver function data or liver pathology was assessed.
The correlation coefficients were compared between ΔLSR (ΔLMR) and ΔLSR (ΔLMR) × LV.
Results.
The correlation coefficient between ΔLSR (ΔLMR) × LV and cholinesterase was significantly higher than that between ΔLSR (ΔLMR) and cholinesterase.
The correlation coefficient between ΔLSR (ΔLMR) × LV and the degree of fibrosis or necroinflammatory activity was significantly lower than that between ΔLSR (ΔLMR) and the degree of fibrosis or necroinflammatory activity.
Conclusion.
The inclusion of liver volume may improve Gd-EOB-DTPA-based predictions of liver function, but not in predictions of liver pathology.
American Psychological Association (APA)
Shimamoto, Dai& Nishie, Akihiro& Asayama, Yoshiki& Ushijima, Yasuhiro& Takayama, Yukihisa& Fujita, Nobuhiro…[et al.]. 2015. MR Prediction of Liver Function and Pathology Using Gd-EOB-DTPA: Effect of Liver Volume Consideration. BioMed Research International،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1054346
Modern Language Association (MLA)
Shimamoto, Dai…[et al.]. MR Prediction of Liver Function and Pathology Using Gd-EOB-DTPA: Effect of Liver Volume Consideration. BioMed Research International No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1054346
American Medical Association (AMA)
Shimamoto, Dai& Nishie, Akihiro& Asayama, Yoshiki& Ushijima, Yasuhiro& Takayama, Yukihisa& Fujita, Nobuhiro…[et al.]. MR Prediction of Liver Function and Pathology Using Gd-EOB-DTPA: Effect of Liver Volume Consideration. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1054346
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054346