Genetic Diversity of Human Adenovirus in Children with Acute Gastroenteritis, Albania, 2013–2015
Joint Authors
La Rosa, G.
Della Libera, S.
Petricca, S.
Iaconelli, M.
Donia, D.
Cenko, F.
Xhelilaj, G.
Divizia, M.
Saccucci, Patrizia
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The objectives of the present study were to assess the occurrence of human adenoviruses (HAdVs) in paediatric patients with gastroenteritis in Albania and to characterize HAdV strains.
Faecal specimens from children admitted with acute gastroenteritis to the Paediatric Hospital in Tirana were screened for HAdV, using broad-range primers targeting the hexon gene, in combination with species-specific primers targeting the fiber gene.
Phylogenetic analysis was then performed to assess the genetic relationships among the different sequences and between the sequences of the samples and those of the prototype strains.
Adenovirus DNA was detected in 33/142 samples (23.2%); 14 belonged to species F (13 HAdV-41 and 1 HAdV-40), 13 to species C (1 HAdV-1, 8 HAdV-2, and 4 HAdV-5), 5 to species B (HAdV-3), and 1 to species A (HAdV-12).
Rotavirus coinfection was present in 9/33 (27.2%) positive samples.
In the remaining 24 positive samples (12 enteric—F species; 12 nonenteric—A, B, or C species), HAdVs were detected as unique viral pathogens, suggesting that HAdV may be an important cause of diarrhoea in children requiring hospitalization.
This is the first study investigating the presence of human adenoviruses (species A–G) as etiologic agents of viral gastroenteritis in children in Albania.
American Psychological Association (APA)
La Rosa, G.& Della Libera, S.& Petricca, S.& Iaconelli, M.& Donia, D.& Saccucci, Patrizia…[et al.]. 2015. Genetic Diversity of Human Adenovirus in Children with Acute Gastroenteritis, Albania, 2013–2015. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1054351
Modern Language Association (MLA)
La Rosa, G.…[et al.]. Genetic Diversity of Human Adenovirus in Children with Acute Gastroenteritis, Albania, 2013–2015. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1054351
American Medical Association (AMA)
La Rosa, G.& Della Libera, S.& Petricca, S.& Iaconelli, M.& Donia, D.& Saccucci, Patrizia…[et al.]. Genetic Diversity of Human Adenovirus in Children with Acute Gastroenteritis, Albania, 2013–2015. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1054351
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054351