Validation of Urine Test for Detection of Helicobacter pylori Infection in Indonesian Population
Joint Authors
Syam, Ari Fahrial
Miftahussurur, Muhammad
Uwan, Willy Brodus
Simanjuntak, David
Uchida, Tomohisa
Yamaoka, Yoshio
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-28
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
We measured the accuracy of the urine test (RAPIRUN) for detection of Helicobacter pylori infection in Indonesia (Jakarta, Pontianak, and Jayapura) using histology confirmed by immunohistochemistry and/or culture as gold standards.
We also used immunohistochemistry to identify CagA phenotype and analyzed H.
pylori CagA diversity in Indonesia.
The overall prevalence of H.
pylori infection in 88 consecutive dyspeptic patients based on the urine test was 15.9% (14/88), 38.1% for patients in Jayapura that had higher prevalence of H.
pylori infection than that in Jakarta (9.7%, P = 0.02 ) and Pontianak (8.3%, P = 0.006 ).
Overall sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of RAPIRUN were 83.3%, 94.7%, 71.4%, 97.3%, and 93.2%, respectively.
All of the H.
pylori-positive patients were immunoreactive for anti-CagA antibody but not immunoreactive for East Asian specific anti-CagA antibody in all H.
pylori-positive subjects.
We confirmed the high accuracy of RAPIRUN in Indonesian population.
In general, we found less virulent type of H.
pylori in Indonesia, which partly explained the low incidence gastric cancer in Indonesia.
American Psychological Association (APA)
Syam, Ari Fahrial& Miftahussurur, Muhammad& Uwan, Willy Brodus& Simanjuntak, David& Uchida, Tomohisa& Yamaoka, Yoshio. 2015. Validation of Urine Test for Detection of Helicobacter pylori Infection in Indonesian Population. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1054387
Modern Language Association (MLA)
Syam, Ari Fahrial…[et al.]. Validation of Urine Test for Detection of Helicobacter pylori Infection in Indonesian Population. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1054387
American Medical Association (AMA)
Syam, Ari Fahrial& Miftahussurur, Muhammad& Uwan, Willy Brodus& Simanjuntak, David& Uchida, Tomohisa& Yamaoka, Yoshio. Validation of Urine Test for Detection of Helicobacter pylori Infection in Indonesian Population. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1054387
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054387