MicroRNAs as Important Players and Biomarkers in Oral Carcinogenesis
Joint Authors
Min, Anjie
Zhu, Chao
Peng, Shuping
Rajthala, Saroj
Costea, Daniela Elena
Sapkota, Dipak
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-04
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Oral cancer, represented mainly by oral squamous cell carcinoma (OSCC), is the eighth most common type of human cancer worldwide.
The number of new OSCC cases is increasing worldwide, especially in the low-income countries, and the prognosis remains poor in spite of recent advances in the diagnostic and therapeutic modalities.
MicroRNAs (miRNAs), 18–25 nucleotides long noncoding RNA molecules, have recently gained significant attention as potential regulators and biomarkers for carcinogenesis.
Recent data show that several miRNAs are deregulated in OSCC, and they have either a tumor suppressive or an oncogenic role in oral carcinogenesis.
This review summarizes current knowledge on the role of miRNAs as tumor promotors or tumor suppressors in OSCC development and discusses their potential value as diagnostic and prognostic markers in OSCC.
American Psychological Association (APA)
Min, Anjie& Zhu, Chao& Peng, Shuping& Rajthala, Saroj& Costea, Daniela Elena& Sapkota, Dipak. 2015. MicroRNAs as Important Players and Biomarkers in Oral Carcinogenesis. BioMed Research International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1054549
Modern Language Association (MLA)
Min, Anjie…[et al.]. MicroRNAs as Important Players and Biomarkers in Oral Carcinogenesis. BioMed Research International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1054549
American Medical Association (AMA)
Min, Anjie& Zhu, Chao& Peng, Shuping& Rajthala, Saroj& Costea, Daniela Elena& Sapkota, Dipak. MicroRNAs as Important Players and Biomarkers in Oral Carcinogenesis. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1054549
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054549