![](/images/graphics-bg.png)
Lower Urinary Tract Symptoms Are Associated with Increased Risk of Dementia among the Elderly: A Nationwide Study
Joint Authors
Wu, Ming-Ping
Chiang, Chi-Hsiang
Ho, Chung-Han
Weng, Shih-Feng
Hsieh, Wan-Ting
Hsu, Ya-Wen
Chen, Ping-Jen
Huang, Chien-Cheng
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-28
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Studies show a strong association between dementia and lower urinary tract symptoms (LUTS).
The aim of this study was to investigate whether LUTS are a risk factor for cognitive impairment.
We enrolled 50-year-old and older subjects with LUTS (LUTS[+]) (n=6801) and controls without LUTS (LUTS[−]) (n=20,403) from Taiwan’s National Health Insurance Research Database.
LUTS, dementia, and other confounding factors are defined by International Classification of Diseases, Ninth Revision, Clinical Modification Codes.
Participants were recruited from 2000 to 2004 and then followed up until death or the end of 2011.
The outcome was the onset of dementia, which was assessed using Poisson regression analysis, Cox hazards models, and Kaplan-Meier survival curves.
The incidence of dementia was significantly higher in the LUTS[+] group than in the LUTS[−] group (124.76 versus 77.59/1000 person-years).
The increased risk of dementia related to LUTS remained significant after adjustment for potential confounders (adjusted hazard ratio (AHR): 1.61, 95% confidence interval (CI) 1.47–1.76, P<0.0001) and higher than that related to cerebrovascular disease (AHR: 1.43, 95% CI 1.26–1.61, P<0.0001).
The outcome suggests the need for early screening and appropriate intervention to help prevent cognitive impairment of patients with LUTS.
American Psychological Association (APA)
Chiang, Chi-Hsiang& Wu, Ming-Ping& Ho, Chung-Han& Weng, Shih-Feng& Huang, Chien-Cheng& Hsieh, Wan-Ting…[et al.]. 2015. Lower Urinary Tract Symptoms Are Associated with Increased Risk of Dementia among the Elderly: A Nationwide Study. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1054554
Modern Language Association (MLA)
Chiang, Chi-Hsiang…[et al.]. Lower Urinary Tract Symptoms Are Associated with Increased Risk of Dementia among the Elderly: A Nationwide Study. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1054554
American Medical Association (AMA)
Chiang, Chi-Hsiang& Wu, Ming-Ping& Ho, Chung-Han& Weng, Shih-Feng& Huang, Chien-Cheng& Hsieh, Wan-Ting…[et al.]. Lower Urinary Tract Symptoms Are Associated with Increased Risk of Dementia among the Elderly: A Nationwide Study. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1054554
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054554