Current and Potential Applications of Host-Defense Peptides and Proteins in Urology
Joint Authors
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-01
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The use of antibiotics has become increasingly disfavored as more multidrug resistant pathogens are on the rise.
A promising alternative to the use of these conventional drugs includes antimicrobial peptides or host-defense peptides.
These peptides typically consist of short amino acid chains with a net cationic charge and a substantial portion of hydrophobic residues.
They mainly target the bacterial cell membrane but are also capable of translocating through the membrane and target intracellular components, making it difficult for bacteria to gain resistance as multiple essential cellular processes are being targeted.
The use of these peptides in the field of biomedical therapies has been examined, and the different approaches to using them under various settings are constantly being discovered.
In this review, we discuss the current and potential applications of these host-defense peptides in the field of urology.
Besides the use of these peptides as antimicrobial agents, the value of these biological molecules has recently been expanded to their use as antitumor and anti-kidney-stone agents.
American Psychological Association (APA)
Lo, Joey Chor Yee& Lange, Dirk. 2015. Current and Potential Applications of Host-Defense Peptides and Proteins in Urology. BioMed Research International،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1054555
Modern Language Association (MLA)
Lo, Joey Chor Yee& Lange, Dirk. Current and Potential Applications of Host-Defense Peptides and Proteins in Urology. BioMed Research International No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1054555
American Medical Association (AMA)
Lo, Joey Chor Yee& Lange, Dirk. Current and Potential Applications of Host-Defense Peptides and Proteins in Urology. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1054555
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054555