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Dental Stem Cell Migration on Pulp Ceiling Cavities Filled with MTA, Dentin Chips, or Bio-Oss
Joint Authors
Lymperi, Stefania
Taraslia, Vasiliki
Tsatsoulis, Ioannis N.
Samara, Athina
Velentzas, Athanasios D.
Agrafioti, Anastasia
Anastasiadou, Ema
Kontakiotis, Evangelos
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-03
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
MTA, Bio-Oss, and dentin chips have been successfully used in endodontics.
The aim of this study was to assess the adhesion and migration of dental stem cells on human pulp ceiling cavities filled with these endodontic materials in an experimental model, which mimics the clinical conditions of regenerative endodontics.
Cavities were formed, by a homemade mold, on untouched third molars, filled with endodontic materials, and observed with electron microscopy.
Cells were seeded on cavities’ surface and their morphology and number were analysed.
The phenomenon of tropism was assessed in a migration assay.
All three materials demonstrated appropriate microstructures for cell attachment.
Cells grew on all reagents, but they showed a differential morphology.
Moreover, variations were observed when comparing cells numbers on cavity’s filling versus the surrounding dentine disc.
The highest number of cells was recorded on dentin chips whereas the opposite was true for Bio-Oss.
This was confirmed in the migration assay where a statistically significant lower number of cells migrated towards Bio-Oss as compared to MTA and dentin chips.
This study highlights that MTA and dentin chips have a greater potential compared to Bio-Oss regarding the attraction of dental stem cells and are good candidates for bioengineered pulp regeneration.
American Psychological Association (APA)
Lymperi, Stefania& Taraslia, Vasiliki& Tsatsoulis, Ioannis N.& Samara, Athina& Velentzas, Athanasios D.& Agrafioti, Anastasia…[et al.]. 2015. Dental Stem Cell Migration on Pulp Ceiling Cavities Filled with MTA, Dentin Chips, or Bio-Oss. BioMed Research International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1054561
Modern Language Association (MLA)
Lymperi, Stefania…[et al.]. Dental Stem Cell Migration on Pulp Ceiling Cavities Filled with MTA, Dentin Chips, or Bio-Oss. BioMed Research International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1054561
American Medical Association (AMA)
Lymperi, Stefania& Taraslia, Vasiliki& Tsatsoulis, Ioannis N.& Samara, Athina& Velentzas, Athanasios D.& Agrafioti, Anastasia…[et al.]. Dental Stem Cell Migration on Pulp Ceiling Cavities Filled with MTA, Dentin Chips, or Bio-Oss. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1054561
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054561