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Association between Hyperhomocysteinemia and Thyroid Hormones in Euthyroid Diabetic Subjects
Joint Authors
Zhang, Yun
Wang, Qiong
Li, Quanzhong
Lu, Ping
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-21
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objectives.
The concept now emerging is that higher thyroid-stimulating hormone (TSH) and lower thyroid hormone levels within the euthyroid range may adversely affect atherosclerosis.
The present study aimed to investigate the potential associations between thyroid parameters and hyperhomocysteinaemia in a cohort of euthyroid diabetic subjects.
Material and Methods.
Two hundred and seventy-three euthyroid diabetic subjects (167 males and 106 females) were consecutively recruited in this cross-sectional study.
Clinical and biomedical data was collected.
Results.
TSH level was higher in females than males.
Compared to normal-homocysteine group, hyperhomocysteinaemia group was more likely to be elderly, males, with longer diabetes history, and with lower diastolic blood pressure.
Free thyroxine (FT4) level was lower in hyperhomocysteinaemia group than in normal-homocysteine group; however, it was not statistically significant.
Adjusted for age, sex, body mass index, duration of diabetes, blood pressure, fasting glucose, total cholesterol, and triglyceride in logistic regression analyses, hyperhomocysteinaemia was significantly correlated with FT4 ( P = 0.0 21 ).
No significant association was found with TSH or free triiodothyronine.
When analyzed in subjects with TSH < 2.5 uIU/mL separately, we got similar results.
Conclusions.
In conclusion, we identified a relation between hyperhomocysteinemia and FT4 in a group of euthyroid diabetic patients.
American Psychological Association (APA)
Zhang, Yun& Wang, Qiong& Li, Quanzhong& Lu, Ping. 2015. Association between Hyperhomocysteinemia and Thyroid Hormones in Euthyroid Diabetic Subjects. BioMed Research International،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1054588
Modern Language Association (MLA)
Zhang, Yun…[et al.]. Association between Hyperhomocysteinemia and Thyroid Hormones in Euthyroid Diabetic Subjects. BioMed Research International No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1054588
American Medical Association (AMA)
Zhang, Yun& Wang, Qiong& Li, Quanzhong& Lu, Ping. Association between Hyperhomocysteinemia and Thyroid Hormones in Euthyroid Diabetic Subjects. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1054588
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054588