Cholestasis in neonates and infants
Author
Source
The Egyptian Journal of Medical Human Genetics
Issue
Vol. 9, Issue 2 (30 Nov. 2008), pp.135-147, 13 p.
Publisher
Egyptian Society of Human Genetics
Publication Date
2008-11-30
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Topics
Abstract EN
The term cholestasis is Greek in origin, meaning bile stoppage.
In its most overt form, cholestasis presents to the clinician as jaundice.
However, jaundice is only the tip of the iceberg of cholestasis liver disease.
The incidence of neonatal cholestasis is estimated around 1 in 2500 live births.
Cholestasis must always be considered in newborns with prolonged jaundice lasting more than 14-21 days.
There are a number of contributing factors for neonatal cholestasis which include bile duct abnormalities ; infections, such as sepsis and urinary tract infections ; inherited and metabolic disorders ; endocrine disorders; chromosomal disorders ; toxicity from parenteral nutrition ; vascular disorders ; prematurity, lack of enteral feedings and medications.
The most common causes of neonatal cholestasis are biliary atresia and idiopathic neonatal hepatitis.
The Aim : of this review is to discuss the pathophysiology, causes and approach of cholestasis.
American Psychological Association (APA)
al-Faramawy, Amal. 2008. Cholestasis in neonates and infants. The Egyptian Journal of Medical Human Genetics،Vol. 9, no. 2, pp.135-147.
https://search.emarefa.net/detail/BIM-105460
Modern Language Association (MLA)
al-Faramawy, Amal. Cholestasis in neonates and infants. The Egyptian Journal of Medical Human Genetics Vol. 9, no. 2 (Nov. 2008), pp.135-147.
https://search.emarefa.net/detail/BIM-105460
American Medical Association (AMA)
al-Faramawy, Amal. Cholestasis in neonates and infants. The Egyptian Journal of Medical Human Genetics. 2008. Vol. 9, no. 2, pp.135-147.
https://search.emarefa.net/detail/BIM-105460
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 146 -147
Record ID
BIM-105460