Network Comparison of Inflammation in Colorectal Cancer and Alzheimer’s Disease
Joint Authors
Park, Sungjin
Yu, Seok Jong
Cho, Yongseong
Balch, Curt
Kim, Yon Hui
Nam, Seungyoon
Lee, Jinhyuk
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-26
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Recently, a large clinical study revealed an inverse correlation of individual risk of cancer versus Alzheimer’s disease (AD).
However, no explanation exists for this anticorrelation at the molecular level; however, inflammation is crucial to the pathogenesis of both diseases, necessitating a need to understand differing signaling usage during inflammatory responses distinct to both diseases.
Using a subpathway analysis approach, we identified numerous well-known and previously unknown pathways enriched in datasets from both diseases.
Here, we present the quantitative importance of the inflammatory response in the two disease pathologies and summarize signal transduction pathways common to both diseases that are affected by inflammation.
American Psychological Association (APA)
Park, Sungjin& Yu, Seok Jong& Cho, Yongseong& Balch, Curt& Lee, Jinhyuk& Kim, Yon Hui…[et al.]. 2015. Network Comparison of Inflammation in Colorectal Cancer and Alzheimer’s Disease. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1054625
Modern Language Association (MLA)
Park, Sungjin…[et al.]. Network Comparison of Inflammation in Colorectal Cancer and Alzheimer’s Disease. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1054625
American Medical Association (AMA)
Park, Sungjin& Yu, Seok Jong& Cho, Yongseong& Balch, Curt& Lee, Jinhyuk& Kim, Yon Hui…[et al.]. Network Comparison of Inflammation in Colorectal Cancer and Alzheimer’s Disease. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1054625
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054625