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Transfection of Platyhelminthes
Joint Authors
Carrero, Julio César
Laclette, Juan Pedro
Moguel, Bárbara
Bobes, Raúl J.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-18
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Flatworms are one of the most diverse groups within Lophotrochozoa with more than 20,000 known species, distributed worldwide in different ecosystems, from the free-living organisms in the seas and lakes to highly specialized parasites living in a variety of hosts, including humans.
Several infections caused by flatworms are considered major neglected diseases affecting countries in the Americas, Asia, and Africa.
For several decades, a particular interest on free-living flatworms was due to their ability to regenerate considerable portions of the body, implying the presence of germ cells that could be important for medicine.
The relevance of reverse genetics for this group is clear; understanding the phenotypic characteristics of specific genes will shed light on developmental traits of free-living and parasite worms.
The genetic manipulation of flatworms will allow learning more about the mechanisms for tissue regeneration, designing new and more effective anthelmintic drugs, and explaining the host-parasite molecular crosstalk so far partially inaccessible for experimentation.
In this review, availability of transfection techniques is analyzed across flatworms, from the initial transient achievements to the stable manipulations now developed for free-living and parasite species.
American Psychological Association (APA)
Moguel, Bárbara& Bobes, Raúl J.& Carrero, Julio César& Laclette, Juan Pedro. 2015. Transfection of Platyhelminthes. BioMed Research International،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1054627
Modern Language Association (MLA)
Moguel, Bárbara…[et al.]. Transfection of Platyhelminthes. BioMed Research International No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1054627
American Medical Association (AMA)
Moguel, Bárbara& Bobes, Raúl J.& Carrero, Julio César& Laclette, Juan Pedro. Transfection of Platyhelminthes. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1054627
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054627