Comparison of Intravoxel Incoherent Motion Diffusion-Weighted MR Imaging and Arterial Spin Labeling MR Imaging in Gliomas
Joint Authors
Zhang, Zhiqiang
Lin, Yuankai
Li, Jianrui
Xu, Qiang
Zhou, Zhenyu
Zhang, Zhongping
Zhang, Yong
Zhang, Zongjun
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-05
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Gliomas grading is important for treatment plan; we aimed to investigate the application of intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI) in gliomas grading, by comparing with the three-dimensional pseudocontinuous arterial spin labeling (3D pCASL).
24 patients (13 high grade gliomas and 11 low grade gliomas) underwent IVIM DWI and 3D pCASL imaging before operation; maps of fast diffusion coefficient (D∗), slow diffusion coefficient (D), fractional perfusion-related volume (f), and apparent diffusion coefficient (ADC) as well as cerebral blood flow (CBF) were calculated and then coregistered to generate the corresponding parameter values.
We found CBF and D∗ were higher in the high grade gliomas, whereas ADC, D, and f were lower (all P<0.05).
In differentiating the high from low grade gliomas, the maximum areas under the curves (AUC) of D∗, CBF, and ADC were 0.857, 0.85, and 0.902, respectively.
CBF was negatively correlated with f in tumor (r=-0.619, P=0.001).
ADC was positively correlated with D in both tumor and white matter (r=0.887, P=0.000 and r=0.824, P=0.000, resp.).
There was no correlation between CBF and D∗ in both tumor and white matter (P>0.05).
IVIM DWI showed more efficiency than 3D pCASL but less validity than conventional DWI in differentiating the high from low grade gliomas.
American Psychological Association (APA)
Lin, Yuankai& Li, Jianrui& Zhang, Zhiqiang& Xu, Qiang& Zhou, Zhenyu& Zhang, Zhongping…[et al.]. 2015. Comparison of Intravoxel Incoherent Motion Diffusion-Weighted MR Imaging and Arterial Spin Labeling MR Imaging in Gliomas. BioMed Research International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1054689
Modern Language Association (MLA)
Lin, Yuankai…[et al.]. Comparison of Intravoxel Incoherent Motion Diffusion-Weighted MR Imaging and Arterial Spin Labeling MR Imaging in Gliomas. BioMed Research International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1054689
American Medical Association (AMA)
Lin, Yuankai& Li, Jianrui& Zhang, Zhiqiang& Xu, Qiang& Zhou, Zhenyu& Zhang, Zhongping…[et al.]. Comparison of Intravoxel Incoherent Motion Diffusion-Weighted MR Imaging and Arterial Spin Labeling MR Imaging in Gliomas. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1054689
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054689