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Evaluation of the Contribution of Signals Originating from Large Blood Vessels to Signals of Functionally Specific Brain Areas
Joint Authors
Chung, Jun-Young
Sung, Yul-Wan
Ogawa, Seiji
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-27
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The fusiform face area (FFA) is known to play a pivotal role in face processing.
The FFA is located in the ventral region, at the base of the brain, through which large blood vessels run.
The location of the FFA via functional MRI (fMRI) may be influenced by these large blood vessels.
Responses of large blood vessels may not exactly correspond to neuronal activity in a target area, because they may be diluted and influenced by inflow effects.
In this study, we investigated the effects of large blood vessels in the FFA, that is, whether the FFA includes large blood vessels and/or whether inflow signals contribute to fMRI signals of the FFA.
For this purpose, we used susceptibility-weighted imaging (SWI) sequences to visualize large blood vessels and dual-echo gradient-echo echo-planar imaging (GE-EPI) to measure inflow effects.
These results showed that the location and response signals of the FFA were not influenced by large blood vessels or inflow effects, although large blood vessels were located near the FFA.
Therefore, the data from the FFA obtained by individual analysis were robust to large blood vessels but leaving a warning that the data obtained by group analysis may be prone to large blood vessels.
American Psychological Association (APA)
Chung, Jun-Young& Sung, Yul-Wan& Ogawa, Seiji. 2015. Evaluation of the Contribution of Signals Originating from Large Blood Vessels to Signals of Functionally Specific Brain Areas. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1054690
Modern Language Association (MLA)
Chung, Jun-Young…[et al.]. Evaluation of the Contribution of Signals Originating from Large Blood Vessels to Signals of Functionally Specific Brain Areas. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1054690
American Medical Association (AMA)
Chung, Jun-Young& Sung, Yul-Wan& Ogawa, Seiji. Evaluation of the Contribution of Signals Originating from Large Blood Vessels to Signals of Functionally Specific Brain Areas. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1054690
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054690