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Integration of DCE-MRI and DW-MRI Quantitative Parameters for Breast Lesion Classification
Joint Authors
Filice, Salvatore
Fusco, Roberta
Amato, Daniela Maria
Di Bonito, Maurizio
D’Aiuto, Massimiliano
Capasso, Immacolata
Rinaldo, Massimo
Petrillo, Antonella
Granata, Vincenza
Catalano, Orlando
Sansone, Mario
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-03
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Objective.
The purpose of our study was to evaluate the diagnostic value of an imaging protocol combining dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted MRI (DW-MRI) in patients with suspicious breast lesions.
Materials and Methods.
A total of 31 breast lesions (15 malignant and 16 benign proved by histological examination) in 26 female patients were included in this study.
For both DCE-MRI and DW-MRI model free and model based parameters were computed pixel by pixel on manually segmented ROIs.
Statistical procedures included conventional linear analysis and more advanced techniques for classification of lesions in benign and malignant.
Results.
Our findings indicated no strong correlation between DCE-MRI and DW-MRI parameters.
Results of classification analysis show that combining of DCE parameters or DW-MRI parameter, in comparison of single feature, does not yield a dramatic improvement of sensitivity and specificity of the two techniques alone.
The best performance was obtained considering a full combination of all features.
Moreover, the classification results combining all features are dominated by DCE-MRI features alone.
Conclusion.
The combination of DWI and DCE-MRI does not show a potential to dramatically increase the sensitivity and specificity of breast MRI.
DCE-MRI alone gave the same performance as in combination with DW-MRI.
American Psychological Association (APA)
Fusco, Roberta& Sansone, Mario& Filice, Salvatore& Granata, Vincenza& Catalano, Orlando& Amato, Daniela Maria…[et al.]. 2015. Integration of DCE-MRI and DW-MRI Quantitative Parameters for Breast Lesion Classification. BioMed Research International،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1054700
Modern Language Association (MLA)
Fusco, Roberta…[et al.]. Integration of DCE-MRI and DW-MRI Quantitative Parameters for Breast Lesion Classification. BioMed Research International No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1054700
American Medical Association (AMA)
Fusco, Roberta& Sansone, Mario& Filice, Salvatore& Granata, Vincenza& Catalano, Orlando& Amato, Daniela Maria…[et al.]. Integration of DCE-MRI and DW-MRI Quantitative Parameters for Breast Lesion Classification. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1054700
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054700