Autologous Bone Marrow Mesenchymal Stem Cells Associated with Tantalum Rod Implantation and Vascularized Iliac Grafting for the Treatment of End-Stage Osteonecrosis of the Femoral Head

Joint Authors

Zhao, Dewei
Liu, Baoyi
Wang, Benjie
Yang, Lei
Xie, Hui
Huang, Shibo
Zhang, Yao
Wei, Xiaowei

Source

BioMed Research International

Issue

Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2015-02-23

Country of Publication

Egypt

No. of Pages

9

Main Subjects

Medicine

Abstract EN

Tantalum rod implantation with vascularized iliac grafting has been reported to be an effective method for the treatment of young patients with osteonecrosis of the femoral head (ONFH) to avert the need for total hip arthroplasty (THA).

However, there have been unsatisfactory success rates for end-stage ONFH.

The authors describe a modified technique using bone marrow mesenchymal stem cells (BMMSCs) associated with porous tantalum rod implantation combined with vascularized iliac grafting for the treatment of end-stage ONFH.

A total of 24 patients (31 hips) with end-stage ONFH were treated with surgery; ARCO IIIc stage was observed in 19 hips and ARCO IV stage was observed in 12 hips.

All patients were followed for a mean time of 64.35 ± 13.03 months (range 26–78).

Operations on only five hips were converted to THA.

The joint-preserving success rate of the entire group was 89.47% for ARCO stage IIIc and 75% for ARCO stage IV.

The mean Harris hip score of the 31 hips improved significantly from 38.74 ± 5.88 points (range 22–50) to 77.23 ± 14.75 points (range 33–95).

This intervention was safe and effective in delaying or avoiding total hip replacement for end-stage ONFH.

American Psychological Association (APA)

Zhao, Dewei& Liu, Baoyi& Wang, Benjie& Yang, Lei& Xie, Hui& Huang, Shibo…[et al.]. 2015. Autologous Bone Marrow Mesenchymal Stem Cells Associated with Tantalum Rod Implantation and Vascularized Iliac Grafting for the Treatment of End-Stage Osteonecrosis of the Femoral Head. BioMed Research International،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1054715

Modern Language Association (MLA)

Zhao, Dewei…[et al.]. Autologous Bone Marrow Mesenchymal Stem Cells Associated with Tantalum Rod Implantation and Vascularized Iliac Grafting for the Treatment of End-Stage Osteonecrosis of the Femoral Head. BioMed Research International No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1054715

American Medical Association (AMA)

Zhao, Dewei& Liu, Baoyi& Wang, Benjie& Yang, Lei& Xie, Hui& Huang, Shibo…[et al.]. Autologous Bone Marrow Mesenchymal Stem Cells Associated with Tantalum Rod Implantation and Vascularized Iliac Grafting for the Treatment of End-Stage Osteonecrosis of the Femoral Head. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1054715

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1054715