Autologous Bone Marrow Mesenchymal Stem Cells Associated with Tantalum Rod Implantation and Vascularized Iliac Grafting for the Treatment of End-Stage Osteonecrosis of the Femoral Head
Joint Authors
Zhao, Dewei
Liu, Baoyi
Wang, Benjie
Yang, Lei
Xie, Hui
Huang, Shibo
Zhang, Yao
Wei, Xiaowei
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-23
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Tantalum rod implantation with vascularized iliac grafting has been reported to be an effective method for the treatment of young patients with osteonecrosis of the femoral head (ONFH) to avert the need for total hip arthroplasty (THA).
However, there have been unsatisfactory success rates for end-stage ONFH.
The authors describe a modified technique using bone marrow mesenchymal stem cells (BMMSCs) associated with porous tantalum rod implantation combined with vascularized iliac grafting for the treatment of end-stage ONFH.
A total of 24 patients (31 hips) with end-stage ONFH were treated with surgery; ARCO IIIc stage was observed in 19 hips and ARCO IV stage was observed in 12 hips.
All patients were followed for a mean time of 64.35 ± 13.03 months (range 26–78).
Operations on only five hips were converted to THA.
The joint-preserving success rate of the entire group was 89.47% for ARCO stage IIIc and 75% for ARCO stage IV.
The mean Harris hip score of the 31 hips improved significantly from 38.74 ± 5.88 points (range 22–50) to 77.23 ± 14.75 points (range 33–95).
This intervention was safe and effective in delaying or avoiding total hip replacement for end-stage ONFH.
American Psychological Association (APA)
Zhao, Dewei& Liu, Baoyi& Wang, Benjie& Yang, Lei& Xie, Hui& Huang, Shibo…[et al.]. 2015. Autologous Bone Marrow Mesenchymal Stem Cells Associated with Tantalum Rod Implantation and Vascularized Iliac Grafting for the Treatment of End-Stage Osteonecrosis of the Femoral Head. BioMed Research International،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1054715
Modern Language Association (MLA)
Zhao, Dewei…[et al.]. Autologous Bone Marrow Mesenchymal Stem Cells Associated with Tantalum Rod Implantation and Vascularized Iliac Grafting for the Treatment of End-Stage Osteonecrosis of the Femoral Head. BioMed Research International No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1054715
American Medical Association (AMA)
Zhao, Dewei& Liu, Baoyi& Wang, Benjie& Yang, Lei& Xie, Hui& Huang, Shibo…[et al.]. Autologous Bone Marrow Mesenchymal Stem Cells Associated with Tantalum Rod Implantation and Vascularized Iliac Grafting for the Treatment of End-Stage Osteonecrosis of the Femoral Head. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1054715
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054715