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Adenocarcinoma with BAC Features Presented as the Nonsolid Nodule Is Prone to Be False-Negative on 18F-FDG PETCT
Joint Authors
Wu, Hu-bing
Wang, Lijuan
Wang, Quan-shi
Han, Yan-jian
Li, Hong-sheng
Zhou, Wen-lan
Tian, Ying
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-24
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
The present study investigated which type of adenocarcinoma with BAC features was prone to be false-negative on 18F-FDG PET/CT.
Materials and Methods.
A retrospective study was performed on 51 consecutive patients with localized adenocarcinoma with BAC features.
CT and PET were assessed for lesion size, GGO percentage, and SUVmax.
Lesions with FDG uptake the same as or more than mediastinal blood-pool activity were considered as PET-positive.
Results.
Of the 51 cases, 19.6% presented as pure GGO nodules, 31.4% as mixed nodules, and 49.0% as solid nodules.
None of the pure GGO nodules was 18F-FDG avid, compared with 37.5% of mixed nodules and 96.0% of solid nodules (χ2=31.55, P=0.000).
In the mixed nodule group, SUVmax was negatively correlated with GGO percentage (r=-0.588; P=0.021).
The positive detection rate of 18F-FDG PET/CT was 50.0%, 55.6%, and 100% in tumors 1.1–2.0 cm, 2.1–3.0 cm, and >3.0 cm in diameter, respectively (χ2=5.815, P=0.055).
General linear model factor analysis showed that the GGO was an important factor contributing to false-negative PET/CT results (F=23.992, P=0.000), but lesion size was not (F=0.602, P=0.866).
Conclusions.
The present study indicated that the adenocarcinoma with BAC features presented as nonsolid nodule is prone to be false negative on 18F-FDG PET/CT.
American Psychological Association (APA)
Wu, Hu-bing& Wang, Lijuan& Wang, Quan-shi& Han, Yan-jian& Li, Hong-sheng& Zhou, Wen-lan…[et al.]. 2015. Adenocarcinoma with BAC Features Presented as the Nonsolid Nodule Is Prone to Be False-Negative on 18F-FDG PETCT. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1054729
Modern Language Association (MLA)
Wu, Hu-bing…[et al.]. Adenocarcinoma with BAC Features Presented as the Nonsolid Nodule Is Prone to Be False-Negative on 18F-FDG PETCT. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1054729
American Medical Association (AMA)
Wu, Hu-bing& Wang, Lijuan& Wang, Quan-shi& Han, Yan-jian& Li, Hong-sheng& Zhou, Wen-lan…[et al.]. Adenocarcinoma with BAC Features Presented as the Nonsolid Nodule Is Prone to Be False-Negative on 18F-FDG PETCT. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1054729
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054729