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In Vivo Anti-Candida Activity of Phenolic Extracts and Compounds: Future Perspectives Focusing on Effective Clinical Interventions
Joint Authors
Martins, Natália
Silva, Sónia
Henriques, Mariana
Ferreira, Isabel C. F. R.
Barros, Lillian
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-24
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Candida species have increasingly deserved a special attention among the medical community.
In spite of the presence of Candida species as a human commensal, alarming rates of local and systemic infections have been observed, varying from moderate to severe impact.
Currently available antifungal drugs have progressively lost their effectiveness, pointing urgently the problem of the microorganisms with acquired-resistance.
Natural matrices are secularly used for numerous purposes, being inclusive and highly effective as antimicrobials.
Increasing evidence gives a particular emphasis to the contribution of phenolic extracts and related individual compounds.
In vitro studies clearly confirm their prominent effects, but the confirmation through in vivo studies, including the involved mechanisms of action, is not so much deepened.
Therefore, the present report aims to provide extensive knowledge about all these aspects, highlighting the most efficient phytochemical formulations, including therapeutic doses.
Further studies need to be incited to deepen knowledge on this area, namely, focused on clinical trials to provide safer and more effective antimicrobials than the current ones.
American Psychological Association (APA)
Martins, Natália& Barros, Lillian& Henriques, Mariana& Silva, Sónia& Ferreira, Isabel C. F. R.. 2015. In Vivo Anti-Candida Activity of Phenolic Extracts and Compounds: Future Perspectives Focusing on Effective Clinical Interventions. BioMed Research International،Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1054740
Modern Language Association (MLA)
Martins, Natália…[et al.]. In Vivo Anti-Candida Activity of Phenolic Extracts and Compounds: Future Perspectives Focusing on Effective Clinical Interventions. BioMed Research International No. 2015 (2015), pp.1-14.
https://search.emarefa.net/detail/BIM-1054740
American Medical Association (AMA)
Martins, Natália& Barros, Lillian& Henriques, Mariana& Silva, Sónia& Ferreira, Isabel C. F. R.. In Vivo Anti-Candida Activity of Phenolic Extracts and Compounds: Future Perspectives Focusing on Effective Clinical Interventions. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1054740
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054740